4-Quinolinecarboxylic acid

Names

[ CAS No. ]:
486-74-8

[ Name ]:
4-Quinolinecarboxylic acid

[Synonym ]:
MFCD00006782
4-Quinolinecarboxylic acid
EINECS 207-640-1
Quinoline-4-carboxylic acid

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
348.7±15.0 °C at 760 mmHg

[ Melting Point ]:
254-255 °C(lit.)

[ Molecular Formula ]:
C₁₀H₇NO₂

[ Molecular Weight ]:
173.168

[ Flash Point ]:
164.7±20.4 °C

[ Exact Mass ]:
173.047684

[ PSA ]:
50.19000

[ LogP ]:
1.99

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.685

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GD3850000

CHEMICAL NAME :: Cinchoninic acid

CAS REGISTRY NUMBER :: 486-74-8

BEILSTEIN REFERENCE NO. :: 0005224

LAST UPDATED :: 199709

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C10-H7-N-O2

MOLECULAR WEIGHT :: 173.18

WISWESSER LINE NOTATION :: T66 BNJ EVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
GD3850000

[ HS Code ]:
2933499090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Time-of-flight accurate mass spectrometry identification of quinoline alkaloids in honey.

Anal. Bioanal. Chem 407 , 6159-70, (2015)

Time-of-flight accurate mass spectrometry (TOF-MS), following a previous chromatographic (gas or liquid chromatography) separation step, is applied to the identification and structural elucidation of ...

Synthesis, characterization and crystal structure of novel mononuclear peroxotungsten(VI) complexes. Insulinomimetic activity of W(VI) and Nb(V) peroxo complexes.

J. Inorg. Biochem. 103(5) , 859-68, (2009)

Two new mononuclear peroxo complexes of tungsten of the formula (gu)(2)[WO(2)(O(2))(2)] (1) and (gu)[WO(O(2))(2)(quin-2-c)] (2a) (where gu(+)=guanidinium ion, CN(3)H(6)(+) and quin-2-c=quinoline-2-car...

Quinoline-4-carboxylic acid.

Acta Crystallogr. C 54 ( Pt 12) , 1883-5, (1998)

The title acid, C10H7NO2, crystallized in the centrosymmetric space group P2(1)/c with one molecule in the asymmetric unit. There is a single hydrogen bond. O-H...N, with a donor-acceptor distance of ...