lepidine

Names

[ CAS No. ]:
491-35-0

[ Name ]:
lepidine

[Synonym ]:
MFCD00006784
4-Methylquinoline
4-Lepidine
4-Methylquinoline,Lepidine
lepidine
4-methyl quinoline
Quinoline, 4-methyl-
Lepidin
EINECS 207-734-2
Quinoline,4-methyl
Cincholepidine
p-Methylquinoline

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
262.0±0.0 °C at 760 mmHg

[ Melting Point ]:
9-10 °C(lit.)

[ Molecular Formula ]:
C₁₀H₉N

[ Molecular Weight ]:
143.185

[ Flash Point ]:
106.1±11.3 °C

[ Exact Mass ]:
143.073502

[ PSA ]:
12.89000

[ LogP ]:
2.54

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.625

[ Water Solubility ]:
Slightly soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OH0316000

CHEMICAL NAME :: Lepidine

CAS REGISTRY NUMBER :: 491-35-0

BEILSTEIN REFERENCE NO. :: 0110926

LAST UPDATED :: 199710

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C10-H9-N

MOLECULAR WEIGHT :: 143.20

WISWESSER LINE NOTATION :: T66 BNJ E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Unscheduled DNA synthesis

TEST SYSTEM :: Rodent - rat Liver

DOSE/DURATION :: 1 mmol/L

REFERENCE :: CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 12,217,1991 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X8311 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 1557 (estimated) No. of Female Employees: 276 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R36/37/38;R68

[ Safety Phrases ]:
S26-S36-S45-S36/37/39

[ RIDADR ]:
2810.0

[ WGK Germany ]:
3

[ RTECS ]:
OH0316000

[ Hazard Class ]:
6.1

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Time-of-flight accurate mass spectrometry identification of quinoline alkaloids in honey.

Anal. Bioanal. Chem 407 , 6159-70, (2015)

Time-of-flight accurate mass spectrometry (TOF-MS), following a previous chromatographic (gas or liquid chromatography) separation step, is applied to the identification and structural elucidation of ...

Direct, catalytic, and regioselective synthesis of 2-alkyl-, aryl-, and alkenyl-substituted N-heterocycles from N-oxides.

Org. Lett. 16(3) , 864-7, (2014)

A one-step transformation of heterocyclic N-oxides to 2-alkyl-, aryl-, and alkenyl-substituted N-heterocycles is described. The success of this broad-scope methodology hinges on the combination of cop...

A Programmed DNA Marker Based on Bis(4-ethynyl-1,8-naphthalimide) and Three-Methane-Bridged Thiazole Orange.

Chemistry 21 , 16623-30, (2015)

Two large conjugated naphthalimide derivatives with or without three-methane-bridged thiazole orange (TO3; i.e., compounds 1 a and 2 a, respectively) were designed and synthesized. The fluorescence of...