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fentoxan

Names

[ CAS No. ]:
495-48-7

[ Name ]:
fentoxan

[Synonym ]:
fentoxan
Azoxybenzene,Fenazox
1,2-diphenyldiazene oxide
Diazene,diphenyl-,1-oxide
Diphenyldiazene oxide
MFCD00019925
Azobenzene,oxide
2-oxo-1,2-diphenylhydrazin-2-ium-1-ide
Azane, oxidophenyl(phenylazanylidene)-, (Z)-
azoxybenzide
EINECS 207-802-1
Diphenyldiazene 1-oxide
[(Z)-Phenyl-NNO-azoxy]benzene
oxido-phenyl-phenyliminoazanium
Fenazox
Azoxybenzol
Benzene,azoxydi
azoxybenzene
Diazene, diphenyl-, 1-oxide

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
336.0±25.0 °C at 760 mmHg

[ Melting Point ]:
32-36 °C

[ Molecular Formula ]:
C12H10N2O

[ Molecular Weight ]:
198.221

[ Flash Point ]:
157.0±23.2 °C

[ Exact Mass ]:
198.079315

[ PSA ]:
41.11000

[ LogP ]:
4.09

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.582

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CO4025000
CHEMICAL NAME :
Azoxybenzene
CAS REGISTRY NUMBER :
495-48-7
LAST UPDATED :
199806
DATA ITEMS CITED :
20
MOLECULAR FORMULA :
C12-H10-N2-O
MOLECULAR WEIGHT :
198.24
WISWESSER LINE NOTATION :
ONR&UNR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
620 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
940 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
515 mg/kg
TOXIC EFFECTS :
Gastrointestinal - other changes Liver - other changes
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1350 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
275 mg/kg
TOXIC EFFECTS :
Gastrointestinal - other changes Kidney, Ureter, Bladder - other changes
TYPE OF TEST :
Micronucleus test
TYPE OF TEST :
Cytogenetic analysis
TYPE OF TEST :
Sperm Morphology

MUTATION DATA

TYPE OF TEST :
Morphological transformation
TEST SYSTEM :
Rodent - hamster Kidney
DOSE/DURATION :
33400 ug/L
REFERENCE :
PMRSDJ Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1981- Volume(issue)/page/year: 1,626,1981

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H332

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/22

[ Safety Phrases ]:
S28A-S28

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
CO4025000

[ HS Code ]:
2927000090

Synthetic Route

Customs

[ HS Code ]: 2927000090

[ Summary ]:
2927000090 other diazo-, azo- or azoxy-compounds。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Reduction of nitroarenes to azoxybenzenes by potassium borohydride in water.

Molecules 16 , 3563-3568, (2011)

The synthesis of the azoxybenzenes by the reduction of nitroarenes with reducing agent potassium borohydride in water was reported for the first time. PEG-400 was used as a phase transfer catalyst and...

[A case of suicide suspected of poisoning from taking some agricultural chemicals].

Nihon Hoigaku. Zasshi 45(2) , 158-65, (1991)

Forensic toxicological examination was performed on a person who was suspected of poisoning by Azomite emulsion (an acaricide), Roundup (a herbicide) and/or unidentified agricultural chemical and died...

[Distribution and metabolism of azoxybenzene in the rat].

Z. Gesamte Hyg. 35(5) , 255-7, (1989)

No sex differences could been shown after absorption and distribution of azoxybenzen in the rat. The highest level occur in the thyroid gland, the adrenals and in the fat tissues. The maximum level wa...


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