Meprylcaine

Names

[ CAS No. ]:
495-70-5

[ Name ]:
Meprylcaine

[Synonym ]:
Benzoesaeure-(2-methyl-2-propylaminopropylester)
Epirocaine
Epirocain
Meprylcainum [INN-Latin]
Meprylcaine [INN]
Oracaine
1-Benzoyloxy-2-methyl-2-propylamino-propan
Meprilcaino [INN-Spanish]
2-Methyl-2-(propylamino)-1-propanol benzoate
MEPRYLCAINE
1-benzoyloxy-2-methyl-2-propylamino-propane

Chemical & Physical Properties

[ Density]:
1g/cm3

[ Boiling Point ]:
329.5ºC at 760mmHg

[ Molecular Formula ]:
C₁₄H₂₁NO₂

[ Molecular Weight ]:
235.32200

[ Flash Point ]:
153.1ºC

[ Exact Mass ]:
235.15700

[ PSA ]:
38.33000

[ LogP ]:
3.01250

[ Vapour Pressure ]:
0.000177mmHg at 25°C

[ Index of Refraction ]:
1.501

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UB8654200

CHEMICAL NAME :: 1-Propanol, 2-methyl-2-(propylamino)-, benzoate (ester)

CAS REGISTRY NUMBER :: 495-70-5

BEILSTEIN REFERENCE NO. :: 2581683

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C14-H21-N-O2

MOLECULAR WEIGHT :: 235.36

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 195 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor

REFERENCE :: TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 9,38,1962

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 470 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor

REFERENCE :: TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 9,38,1962

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 20 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor

REFERENCE :: TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 9,38,1962