2-hydroxy-4-methylvaleric acid

Names

[ CAS No. ]:
498-36-2

[ Name ]:
2-hydroxy-4-methylvaleric acid

[Synonym ]:
2-Hydroxy-4-methylpentanoic acid
2-hydroxy-4-methyl-Valeric acid
Einecs 207-860-8
DL-2-Hydroxy-4-methylpentanoic acid
hydroxyisocaproic acid
2-hydroxy-4-methyl-pentanoicaci
Einecs 233-677-8
Pentanoic acid, 2-hydroxy-4-methyl-
2-HYDROXY-4-METHYL-PENTANOIC ACID
2-HYDROXYISOCAPROIC ACID
2-Hydroxy-4-methylvaleric acid
DL-Leucic Acid
Leucic acid
Leucinic acid
DL-2-Hydroxyisocaproic acid

Biological Activity

[Description]:

Leucic acid is an amino acid metabolite[1].

[Related Catalog]:

Research Areas >> Others

[References]

[1]. Buck, S. B., et al. Total Synthesis and Anti-Tubulin Activity of Epi-C3 Analogues of Cryptophycin-24. Journal of Medicinal Chemistry, 2004. 47(14), 3697–3699.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
251.3±13.0 °C at 760 mmHg

[ Melting Point ]:
78-80ºC

[ Molecular Formula ]:
C₆H₁₂O₃

[ Molecular Weight ]:
132.16

[ Flash Point ]:
120.1±16.3 °C

[ Exact Mass ]:
132.078644

[ PSA ]:
57.53000

[ LogP ]:
0.71

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.458

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
36/37/38-21

[ Safety Phrases ]:
36/37/39-26

[ RIDADR ]:
NONH for all modes of transport

Articles

Lipidomic profiling reveals significant alterations in lipid biochemistry in hypothyroid rat cerebellum and the therapeutic effects of Sini decoction.

J. Ethnopharmacol. 159 , 262-73, (2014)

Hypothyroidism is known to be closely associated with lipid metabolism. Although our previous serum and urine metabonomics studies have provided some clues about the molecular mechanism of hypothyroid...

Metabolic footprinting for investigation of antifungal properties of Lactobacillus paracasei.

Anal. Bioanal. Chem 408 , 83-96, (2016)

Lactic acid bacteria with antifungal properties are applied for biopreservation of food. In order to further our understanding of their antifungal mechanism, there is an ongoing search for bioactive m...

Hydroxy acid metabolites of branched-chain amino acids in amniotic fluid.

Clin. Chim. Acta 140(2) , 157-66, (1984)

A method is described in which ammonia chemical ionization gas chromatography-mass spectrometry was utilized in the selected ion monitoring mode to provide an accurate, selective approach to the quant...