1,3-DIOXANE

Names

[ CAS No. ]:
505-22-6

[ Name ]:
1,3-DIOXANE

[Synonym ]:
EINECS 208-005-1
meta-Dioxane
1,3-dioxalane
m-Dioxin,dihydro
Trimethylene glycol methylene ether
m-Dioxane
1,3-Propanediol formal
1,3-DIOXANE
1,3-Dioxacyclohexane
MFCD00006566

Chemical & Physical Properties

[ Density]:
1.0342

[ Boiling Point ]:
105ºC

[ Melting Point ]:
-42ºC

[ Molecular Formula ]:
C₄H₈O₂

[ Molecular Weight ]:
88.10510

[ Flash Point ]:
59 °F

[ Exact Mass ]:
88.05240

[ PSA ]:
18.46000

[ LogP ]:
0.38080

[ Index of Refraction ]:
n20/D 1.418(lit.)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: JG8224000

CHEMICAL NAME :: m-Dioxane

CAS REGISTRY NUMBER :: 505-22-6

LAST UPDATED :: 199410

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C4-H8-O2

MOLECULAR WEIGHT :: 88.12

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 2080 mg/L

REFERENCE :: EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 10(Suppl 10),1,1987

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H302 + H312 + H332

[ Precautionary Statements ]:
P210-P280

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F,Xn

[ Risk Phrases ]:
11-20/21/22

[ Safety Phrases ]:
S16

[ RIDADR ]:
UN 1165 3/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
JG8224000

[ Packaging Group ]:
II

[ Hazard Class ]:
3.1

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

One-step synthesis of nitrogen-containing medium-sized rings via α-imino diazo intermediates.

Org. Lett. 16(12) , 3232-5, (2014)

Eight- and 9-membered dioxazocines and dioxazonines are readily synthesized starting from N-sulfonyl-1,2,3-triazoles in a single-step procedure. A perfect regioselectivity and generally good yields (u...

The reactivity of molybdenum pentachloride with ethers: routes to the synthesis of Mo(IV)Cl4 adducts, Mo(V) chlorido-alkoxides and Mo(V) oxydo-chlorides.

Dalton Trans. 42(42) , 15226-34, (2013)

The reactivity of molybdenum pentachloride, 1, with a selection of mono- and diethers was investigated at room temperature in a non-coordinating solvent (dichloromethane). The Mo(IV) complex MoCl4(OMe...

Determination of 1,4-Dioxane in the Cape Fear River Watershed by Heated Purge-and-Trap Preconcentration and Gas Chromatography-Mass Spectrometry.

Environ. Sci. Technol. 50 , 2246-54, (2016)

Recent U.S. Environmental Protection Agency data show that 1,4-dioxane is frequently detected in U.S. drinking water derived from both groundwater and surface water. 1,4-Dioxane is a likely human carc...