4-benzyloxyphenyl isocyanate
Names
[ CAS No. ]:
50528-73-9
[ Name ]:
4-benzyloxyphenyl isocyanate
[Synonym ]:
benzyl 4-isocyanatophenyl ether
MFCD00673046
Chemical & Physical Properties
[ Density]:
1.07g/cm3
[ Boiling Point ]:
129 °C0.2 mm Hg(lit.)
[ Melting Point ]:
60-62 °C(lit.)
[ Molecular Formula ]:
C14H11NO2
[ Molecular Weight ]:
225.24300
[ Flash Point ]:
158.5ºC
[ Exact Mass ]:
225.07900
[ PSA ]:
38.66000
[ LogP ]:
3.23290
[ Index of Refraction ]:
1.555
[ Storage condition ]:
0-6°C
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H312-H315-H319-H332-H335
[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn,Xi
[ Risk Phrases ]:
20/21/22-36/37/38
[ Safety Phrases ]:
S26-S36/37/39
[ RIDADR ]:
2206
[ WGK Germany ]:
3
[ HS Code ]:
2929109000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2929109000
[ Summary ]:
2929109000. other isocyanates. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Chemistry 15(13) , 3103-9, (2009)
Catalytic rivals: Both CO(2)-protected tetrahydropyrimidin-2-ylidene-based N-heterocyclic carbenes (NHCs) and Sn(II)-1,3-dimesitylimidazol-2-ylidene, as well as Sn(II)-1,3-dimesitylimidazolin-2-yliden...
Design, synthesis, and biological activity of urea derivatives as anaplastic lymphoma kinase inhibitors.ChemMedChem 6(9) , 1680-92, (2011)
In anaplastic large-cell lymphomas, chromosomal translocations involving the kinase domain of anaplastic lymphoma kinase (ALK), generally fused to the 5' part of the nucleophosmin gene, produce highly...