tert-butyl chloride

Names

[ CAS No. ]:
507-20-0

[ Name ]:
tert-butyl chloride

[Synonym ]:
Propane, 2-chloro-2-methyl-
T-BUTYL CHLORIDE
MFCD00000816
2-Chloro-2-methylpropane
tertiary butyl chloride
1,1-dimethylethyl chloride
2-Chloro-2-methyl-propane
Trimethylchloromethane
Propane,2-chloro-2-methyl
t-Butylchloride
Propane, 2-chloro-2-methyl
1-chloro-1,1-dimethylethane
tert-butyl chloride
Chlorotrimethylmethane
EINECS 208-066-4
tert-Butylchloride
2-Chloroisobutane
t-butylamine

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
50.6±0.0 °C at 760 mmHg

[ Melting Point ]:
-25 °C

[ Molecular Formula ]:
C₄H₉Cl

[ Molecular Weight ]:
92.567

[ Flash Point ]:
18.3±0.0 °C

[ Exact Mass ]:
92.039276

[ LogP ]:
2.20

[ Vapour density ]:
3.2 (vs air)

[ Vapour Pressure ]:
298.6±0.1 mmHg at 25°C

[ Index of Refraction ]:
1.395

[ Stability ]:
Stable. Extremely flammable. Note low flash point. Incompatible with strong oxidizing agents. Vapour, being much denser than air, may travel considerable distances to a source of ignition. Hygroscopic.

[ Water Solubility ]:
SLIGHTLY SOLUBLE

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TX5040000

CHEMICAL NAME :: Propane, 2-chloro-2-methyl-

CAS REGISTRY NUMBER :: 507-20-0

BEILSTEIN REFERENCE NO. :: 1730872

LAST UPDATED :: 199710

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C4-H9-Cl

MOLECULAR WEIGHT :: 92.58

WISWESSER LINE NOTATION :: GX1&1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3000 mg/kg/8W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,1411,1975 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4432 No. of Facilities: 17 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 202 (estimated)

Safety Information

[ Symbol ]:

GHS02

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225

[ Precautionary Statements ]:
P210

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
F:Flammable;

[ Risk Phrases ]:
R11

[ Safety Phrases ]:
S16-S29-S33-S7/9-S9

[ RIDADR ]:
UN 1127 3/PG 2

[ WGK Germany ]:
1

[ RTECS ]:
TX5040000

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
2903199000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2903199000

[ Summary ]:
2903199000 other saturated chlorinated derivatives of acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Evaluation of amino acid ester-based ionic liquids as buffer additives in CE for the separation of 2-arylpropionic acids nonsteroidal anti-inflammatory drugs.

Electrophoresis 35(18) , 2573-8, (2014)

The aim of the present study is the CE performance evaluation for the separation of 2-arylpropionic acid nonsteroidal anti-inflammatory drugs. In particular, the separation of indoprofen, carprofen, k...

MD study of SN1 reactivity of 2-chloro-2-methylpropane in the room-temperature ionic liquid 1-ethyl-3-methylimidazolium hexafluorophosphate.

J. Phys. Chem. B 112(9) , 2637-43, (2008)

The S(N)1 ionization reaction RX --> R(+) + X(-) for 2-chloro-2-methylpropane in ionic liquid 1-ethyl-3-methylimidazolium hexafluorophosphate ([emim](+)P(-)(6)) is studied via molecular dynamics compu...