14-Hydroxy Codeinone
Names
[ CAS No. ]:
508-54-3
[ Name ]:
14-Hydroxy Codeinone
[Synonym ]:
4-(9b-ethyl-5-methoxy-1,2,3,3a,8,9,9a,9b-octahydro-phenanthro[4,5-bcd]furan-3-yl)-morpholine
Morpholine,4-(9bb-ethyl-1,2,3,3ab,8,9,9ab,9b-octahydro-5-methoxyphenanthro[4,5-bcd]furan-3-yl)-(8CI)
Oxycodone impurity D
Morpholine,4-(9b-ethyl-1,2,3,3a,8,9,9a,9b-octahydro-5-methoxyphenanthro[4,5-bcd]furan-3-yl)-,[3S-(3a,3ab,9ab,9bb)]-(9CI)
14-hydroxy-codeinone
Morpholine,4-(9bb-ethyl-1,2,3,3a,8,9,9ab,9b-octahydro-5-methoxyphenanthro[4,5-bcd]furan-3a-yl)-(7CI)
Chemical & Physical Properties
[ Density]:
1.433g/cm3
[ Boiling Point ]:
512.176ºC at 760 mmHg
[ Melting Point ]:
275°C (rough estimate)
[ Molecular Formula ]:
C18H19NO4
[ Molecular Weight ]:
313.34800
[ Flash Point ]:
263.555ºC
[ Exact Mass ]:
313.13100
[ PSA ]:
59.00000
[ LogP ]:
1.35280
[ Index of Refraction ]:
1.684
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GG8225000
- CHEMICAL NAME :
- Codeinone, 14-hydroxy-
- CAS REGISTRY NUMBER :
- 508-54-3
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C18-H19-N-O4
- MOLECULAR WEIGHT :
- 313.38
- WISWESSER LINE NOTATION :
- T B6566 B6/CO 4ABBC R BX FV HO PN DU GHT&&TTJ CQ JO1 P1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 23 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 28ZNAE "Public Health Reports, Supplement." (Washington, DC) Volume(issue)/page/year: 138,27,1938
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 11800 ug/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 16(Suppl),68T,1964
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H300 + H310 + H330
[ Precautionary Statements ]:
Missing Phrase - N15.00950417-P260-P262-P280-P302 + P352 + P310-P304 + P340 + P310
[ RIDADR ]:
NONH for all modes of transport