4,9-EPOXYCEVANE-3-β,4-β,7-α,14,15-α,16-β,20-HEPTOL
Names
[ CAS No. ]:
508-65-6
[ Name ]:
4,9-EPOXYCEVANE-3-β,4-β,7-α,14,15-α,16-β,20-HEPTOL
[Synonym ]:
cevine
SABADININE
Chemical & Physical Properties
[ Density]:
1.49g/cm3
[ Boiling Point ]:
688.2ºC at 760 mmHg
[ Molecular Formula ]:
C27H43NO8
[ Molecular Weight ]:
509.63200
[ Flash Point ]:
370ºC
[ Exact Mass ]:
509.29900
[ PSA ]:
154.08000
[ Index of Refraction ]:
1.679
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- FL4725000
- CHEMICAL NAME :
- Cevane-3-beta,4-beta,7-alpha,14,15-alpha,16-beta,20-h eptol, 4,9-epoxy-
- CAS REGISTRY NUMBER :
- 508-65-6
- BEILSTEIN REFERENCE NO. :
- 0099115
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C27-H43-N-O8
- MOLECULAR WEIGHT :
- 509.71
- WISWESSER LINE NOTATION :
- T J6 H6 E6 D5665/TC& 3ATU C& ON TX C&OTJ CQ EQ FQ GQ IQ I1 M1 U1 A&Q B&Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - excitement
- REFERENCE :
- AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 189,397,1938
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 113,89,1955
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Amphibian - frog
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - excitement
- REFERENCE :
- AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 189,397,1938 *** REVIEWS *** TOXICOLOGY REVIEW LYPHAD Lyon Pharmaceutique. (Medipharly, 12, rue de la Barre, 69002 Lyons, France) V.1- 1950- Volume(issue)/page/year: 26,5,1975