<Suppliers Price>

Hastatoside

Names

[ CAS No. ]:
50816-24-5

[ Name ]:
Hastatoside

[Synonym ]:
Methyl (1S,4aR,7S,7aR)-1-(β-D-glucopyranosyloxy)-4a-hydroxy-7-methyl-5-oxo-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate
Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-4a-hydroxy-7-methyl-5-oxo-, methyl ester, (1S,4aR,7S,7aR)-

Biological Activity

[Description]:

Hastatoside is an iridoid glycoside that is isolated from Verbena officinalis and has a role in promoting sleep[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

[In Vivo]

Hastatoside (0.32-0.64 mmol/kg; oral administration; for 9 hours; male rats of the Sprague-Dawley strain) treatment increases the total time of non-rapid eye movement sleep during a 9-h period, with a lag time of about 3-5 h after the administration at 20. 00 hours (lights-off time). Hastatoside also increases the delta activity during non-rapid eye movement sleep[1]. Animal Model: Male rats of the Sprague-Dawley strain (8 weeks old; 260-280 g)[1] Dosage: 0.32 mmol/kg, 0.48 mmol/kg, 0.64 mmol/kg Administration: Oral administration; for 9 hours Result: Increased the total time of non-rapid eye movement sleep during a 9-h period, with a lag time of about 3-5 h after the administration at 20. 00 hours (lights-off time). Also increased the delta activity during non-rapid eye movement sleep.

[References]

[1]. uki MAKINO, et al. Hastatoside and verbenalin are sleep-promoting

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
653.5±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C17H24O11

[ Molecular Weight ]:
404.366

[ Flash Point ]:
234.8±25.0 °C

[ Exact Mass ]:
404.131866

[ PSA ]:
172.21000

[ LogP ]:
-2.38

[ Vapour Pressure ]:
0.0±4.5 mmHg at 25°C

[ Index of Refraction ]:
1.613

[ Storage condition ]:
2-8C

Related Compounds