2-(Dimethylamino)ethyl (4-chlorphenoxy)acetate
Names
[ CAS No. ]:
51-68-3
[ Name ]:
2-(Dimethylamino)ethyl (4-chlorphenoxy)acetate
[Synonym ]:
EINECS 200-116-3
Clofenoxin
meclofenoxate
DMAE p-chlorophenoxyacetate
Meclophenoxate
centrophenoxine
Clopenoxin
Deanolestere
meclofenaxate
Cetrexin
Proseryl
2-dimethylaminoethyl (4-chlorophenoxy)acetate
Clophenoxate
Licidril
Cerebon
Chemical & Physical Properties
[ Density]:
1.178g/cm3
[ Boiling Point ]:
345.9ºC at 760mmHg
[ Molecular Formula ]:
C12H16ClNO3
[ Molecular Weight ]:
257.71300
[ Flash Point ]:
163ºC
[ Exact Mass ]:
257.08200
[ PSA ]:
38.77000
[ LogP ]:
1.82360
[ Index of Refraction ]:
1.52
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AG0430000
- CHEMICAL NAME :
- Acetic acid, (p-chlorophenoxy)-, 2-(dimethylamino)ethyl ester
- CAS REGISTRY NUMBER :
- 51-68-3
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C12-H16-Cl-N-O3
- MOLECULAR WEIGHT :
- 257.74
- WISWESSER LINE NOTATION :
- GR DO1VO2N1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,386,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,386,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 758 mg/kg
- TOXIC EFFECTS :
- Brain and Coverings - recordings from specific areas of CNS Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory stimulation
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 38,154,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 150 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,386,1972
Safety Information
[ HS Code ]:
2922509090
Synthetic Route
Customs
[ HS Code ]: 2922509090
[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%