Urethane

Names

[ CAS No. ]:
51-79-6

[ Name ]:
Urethane

[Synonym ]:
Ethyl urethane
urethane
Ethyl Carbamate
caproic acid ethyl ester
Carbamic Acid Ethyl Ester
Capronic ether absolute
2-Ethyl Hexanoate
ethyl carbaminate
ethyl n-heptanoate
Carbamate, Ethyl
Ethyl hexoate
Carbamic acid, ethyl ester
Ethyl caproate
EINECS 200-123-1
Ethyl urethan
Carbamic acid, ethyl ester (8CI 9CI)
methyl,methyl carbamate
MFCD00007966
ethyl ester of carbamic acid
Hexanoic acid,ethyl ester
ethyl capronate

Biological Activity

[Description]:

Urethane has been used as an antineoplastic agent and for other medicinal purposes

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Cancer

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
105.7±23.0 °C at 760 mmHg

[ Melting Point ]:
48-50 °C(lit.)

[ Molecular Formula ]:
C₃H₇NO₂

[ Molecular Weight ]:
89.093

[ Flash Point ]:
17.7±22.6 °C

[ Exact Mass ]:
89.047676

[ PSA ]:
52.32000

[ LogP ]:
0.07

[ Vapour density ]:
3.07 (vs air)

[ Vapour Pressure ]:
15.9±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.423

[ Storage condition ]:
Room temperature.

[ Stability ]:
Stable. Incompatible with strong acids, strong bases, strong oxidizing agents.

[ Water Solubility ]:
slightly soluble

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H350

[ Precautionary Statements ]:
P201-P301 + P312 + P330-P308 + P313

[ Personal Protective Equipment ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
T:Toxic

[ Risk Phrases ]:
R45

[ Safety Phrases ]:
S53-S45

[ RIDADR ]:
UN3077 9/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
FA8400000

[ HS Code ]:
2924199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Mechanistic basis of altered morphine disposition in nonalcoholic steatohepatitis.

J. Pharmacol. Exp. Ther. 352(3) , 462-70, (2015)

Morphine is metabolized in humans to morphine-3-glucuronide (M3G) and the pharmacologically active morphine-6-glucuronide (M6G). The hepatobiliary disposition of both metabolites relies upon multidrug...

Loss of presenilin 2 is associated with increased iPLA2 activity and lung tumor development.

Oncogene 33(44) , 5193-200, (2014)

Presenilins are the enzymatic components of γ-secretase complex that cleaves amyloid precursor protein, Notch and β-catenin, which has critical roles in the development of Alzheimer's disease and canc...

The Ca²⁺-calmodulin-Ca²⁺/calmodulin-dependent protein kinase II signaling pathway is involved in oxidative stress-induced mitochondrial permeability transition and apoptosis in isolated rat hepatocytes.

Arch. Toxicol. 88(9) , 1695-709, (2014)

Oxidative stress (OS) is a common event in most hepatopathies, leading to mitochondrial permeability transition pore (MPTP) formation and further exacerbation of both OS from mitochondrial origin and ...