Acetomycin

Names

[ CAS No. ]:
510-18-9

[ Name ]:
Acetomycin

[Synonym ]:
acetomycin

Biological Activity

[Description]:

Acetomycin is an antibiotic. Acetomycin inhibits the growth of CT-8 human colon adenocarcinoma cells (IC50: 1.5 μg/mL) and L1210 murine leukemia cells (IC50: 2.2 μg/mL). Acetomycin can be isolated from actinomycete WP-2661[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Mamber SW, et al. Biological effects of acetomycin. I. Activity against tumor cells in vitro and in vivo. J Antibiot (Tokyo). 1987 Jan;40(1):73-6.

Chemical & Physical Properties

[ Density]:
1.18g/cm3

[ Boiling Point ]:
336.2ºC at 760mmHg

[ Molecular Formula ]:
C₁₀H₁₄O₅

[ Molecular Weight ]:
214.22

[ Flash Point ]:
148.9ºC

[ Exact Mass ]:
214.08400

[ PSA ]:
69.67000

[ LogP ]:
0.66380

[ Index of Refraction ]:
1.466

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AL2850000

CHEMICAL NAME :: Acetomycin

CAS REGISTRY NUMBER :: 510-18-9

BEILSTEIN REFERENCE NO. :: 0174279

LAST UPDATED :: 199709

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C10-H14-O5

MOLECULAR WEIGHT :: 214.24

WISWESSER LINE NOTATION :: T5OVTJ CV1 C1 D1 EOV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978 Volume(issue)/page/year: 2,905,1978

Safety Information

[ HS Code ]:
2932190090

Customs

[ HS Code ]: 2932190090

[ Summary ]:
2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%