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12-Ketodeoxycholic acid

Names

[ CAS No. ]:
5130-29-0

[ Name ]:
12-Ketodeoxycholic acid

[Synonym ]:
Cholic Acid Impurity (3-alpha-Hydroxy-12-Oxo-5-beta-Cholanoic Acid)

Biological Activity

[Description]:

12-Ketodeoxycholic acid is a bile acid, metabolite from kidney. 12-Ketodeoxycholic acid can be a detectable marker for evidence of kidney injury[1]

[Related Catalog]:

Research Areas >> Metabolic Disease

[Target]

IC50: metabolite from kidney


[In Vitro]

Bile acids are produced from conjugation of cholesterol and its incorporation in the bile by the liver for secretion in the intestine[1].

[References]

[1]. Chen H, et al. Metabolomics insights into activated redox signaling and lipid metabolism dysfunction in chronic kidney disease progression.Redox Biol. 2016 Dec;10:168-178.

Chemical & Physical Properties

[ Molecular Formula ]:
C24H38O4

[ Molecular Weight ]:
390.55600

[ Exact Mass ]:
390.27700

[ PSA ]:
74.60000

[ LogP ]:
4.68610

Precursor & DownStream


Related Compounds