1H-Benzimidazol-2-amine,N-butyl-

Names

[ Name ]:
1H-Benzimidazol-2-amine,N-butyl-

[Synonym ]:
2-N-butylamino-1H-benzimidazole
2-n-Butylaminobenzimidazol
N-Butyl-1H-Benzimidazol-2-Amine

Biological Activity

[Description]:

M084 is a benzimidazole derivative. M084 inhibits the mitochondrial respiration, activate mitochondrial unfolded protein response and AMPK, recruites SIR-2.1 and SKN-1, and finally through the transcription factor DAF-16, delays the aging process of C. elegans[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. Ai-Jun Ding, et al. Benzimidazole derivative M084 extends the lifespan of Caenorhabditis elegans in a DAF-16/FOXO-dependent way. Mol Cell Biochem. 2017 Feb;426(1-2):101-109.

Chemical & Physical Properties

[ Density]:
1.153g/cm3

[ Boiling Point ]:
344.8ºC at 760 mmHg

[ Molecular Formula ]:
C₁₁H₁₅N₃

[ Molecular Weight ]:
189.26

[ Flash Point ]:
162.3ºC

[ Exact Mass ]:
189.12700

[ PSA ]:
40.71000

[ LogP ]:
2.84790

[ Index of Refraction ]:
1.653

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%