1-Methyladenine

Names

[ Name ]:
1-Methyladenine

[Synonym ]:
1-METHYLADENINE
1-Methyladenine

Biological Activity

[Description]:

1-Methyladenine is a product of alkylation damage in DNA which can be repaired by damage reversal by oxidative demethylation.

[Related Catalog]:

Natural Products >> Others

Research Areas >> Others

[Target]

Human Endogenous Metabolite

[References]

[1]. Falnes PØ, et al. Repair of 3-methylthymine and 1-methylguanine lesions by bacterial and human AlkB proteins. Nucleic Acids Res. 2004 Dec 1;32(21):6260-7. Print 2004.

[2]. Yang H, et al. Effect of 1-methyladenine on double-helical DNA structures. FEBS Lett. 2008 May 14;582(11):1629-33.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.6 g/cm3

[ Boiling Point ]:
240.1ºC at 760 mmHg

[ Melting Point ]:
> 300ºC

[ Molecular Formula ]:
C₆H₇N₅

[ Molecular Weight ]:
149.15300

[ Flash Point ]:
99ºC

[ Exact Mass ]:
149.07000

[ PSA ]:
69.62000

[ LogP ]:
0.52670

[ Index of Refraction ]:
1.807

[ Storage condition ]:
?20°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S24/25

[ HS Code ]:
2933990090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%