Folin's reagent

Names

[ CAS No. ]:
521-24-4

[ Name ]:
Folin's reagent

[Synonym ]:
Sodium 1,2-Naphthoquinone-4-sulfonate
EINECS 208-308-9
MFCD00001700
Sodium 3,4-dioxo-3,4-dihydronaphthalene-1-sulfonate
Folin's reagent
Sodium 3,4-dioxo-3,4-dihydro-1-naphthalenesulfonate
1-Naphthalenesulfonic acid, 3,4-dihydro-3,4-dioxo-, sodium salt (1:1)
1,2-Naphthoquinone-4-sulfonic Acid Sodium Salt
sodium,3,4-dioxonaphthalene-1-sulfonate

Chemical & Physical Properties

[ Melting Point ]:
289 °C (dec.)(lit.)

[ Molecular Formula ]:
C₁₀H₅NaO₅S

[ Molecular Weight ]:
260.198

[ Exact Mass ]:
259.975525

[ PSA ]:
99.72000

[ LogP ]:
1.41890

[ Storage condition ]:
2-8°C

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
H2O: 50 mg/mL, clear

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QK1490000

CHEMICAL NAME :: 1-Naphthalenesulfonic acid, 3,4-dihydro-3,4-dioxo-, sodium salt

CAS REGISTRY NUMBER :: 521-24-4

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C10-H6-O5-S.Na

MOLECULAR WEIGHT :: 261.21

WISWESSER LINE NOTATION :: L66 BVVJ ESWQ &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 625 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7927 No. of Facilities: 25 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1358 (estimated) No. of Female Employees: 956 (estimated)

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
QK1490000

[ HS Code ]:
2914399090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914399090

[ Summary ]:
2914399090. other aromatic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

A histochemical examination of the staining of kainate-induced neuronal degeneration by anionic dyes.

Biotech. Histochem. 73(5) , 244-54, (1998)

Anionic dyes, notably acid fuchsine, strongly stain the nuclei and cytoplasm of neurons severely damaged by injury or disease. We provide detailed instructions for staining nervous tissue with toluidi...

Spectrophotometric determination of aminomethylbenzoic acid using sodium 1,2-naphthoquinone-4-sulfonate as the chemical derivative chromogenic reagent.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 66(3) , 656-61, (2007)

A new method has been established for the determination of aminomethylbenzoic acid using sodium 1,2-naphthoquinone-4-sulfonate as the chemical derivative chromogenic reagent. This method is based on t...

Spectophotometric methods for determination of cefdinir in pharmaceutical formulations via derivatization with 1,2-naphthoquinone-4-sulfonate and 4-chloro-7-nitrobenzo-2-oxa-1, 3-diazole.

Drug Test. Anal. 4(12) , 991-1000, (2012)

Two new simple, sensitive, accurate, and precise spectrophotometric methods have been developed and validated for the determination of cefdinir (CFD) in bulk drug and in its pharmaceutical formulation...