Dimethyl squarate
Names
[ CAS No. ]:
5222-73-1
[ Name ]:
Dimethyl squarate
[Synonym ]:
Dimethyl squarate
EINECS 220-761-4
3,4-dimethoxycyclobut-3-ene-1,2-dione
3-Cyclobutene-1,2-dione, 3,4-dimethoxy-
MFCD00101316
3,4-Dimethoxy-3-cyclobutene-1,2-dione
Squaric acid dimethyl ester
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
286.1±50.0 °C at 760 mmHg
[ Melting Point ]:
55-57 °C(lit.)
[ Molecular Formula ]:
C6H6O4
[ Molecular Weight ]:
142.109
[ Flash Point ]:
128.0±30.2 °C
[ Exact Mass ]:
142.026611
[ PSA ]:
52.60000
[ LogP ]:
-1.21
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.478
[ Storage condition ]:
0-6°C
MSDS
Safety Information
[ Symbol ]:
GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H317-H334
[ Precautionary Statements ]:
P261-P280-P342 + P311
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R42/43
[ Safety Phrases ]:
S22-S24/25-S26-S36/37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2914509090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2914509090
[ Summary ]:
HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
Articles
PLoS Negl. Trop. Dis. 9 , e0003881, (2015)
Vibrio cholerae is the cause of cholera, a severe watery diarrhea. Protection against cholera is serogroup specific. Serogroup specificity is defined by the O-specific polysaccharide (OSP) component o...
Squaric acid-based peptidic inhibitors of matrix metalloprotease-1.J. Org. Chem. 70(26) , 10792-802, (2005)
[structure: see text] A series of squaric acid-peptide conjugates were synthesized and evaluated as inhibitors of MMP-1. The cyclobut-3-enedione core was substituted at the 3-position with several fun...
Tetrahedron Lett. 34 , 6177, (1993)