Coproporphyrin I

Names

[ CAS No. ]:
531-14-6

[ Name ]:
Coproporphyrin I

[Synonym ]:
Coproporphyrin I
coproporphyrin-I tetracarboxylic acid
coproporphyrine I
coproporphyrin I-3,8,13,18-tetramethyl-21H,23H-porphine-2,7,12,17-tetrapropionic acid
3,8,13,18-tetramethyl-21H,23H-porphyrin 2,7,12,17-tetrapropionic acid
3,8,13,18-Tetramethyl-21H,23H-porphine-2,7,12,17-tetrapropionic acid

Biological Activity

[Description]:

Coproporphyrin I is an endogenous metabolite present in Urine and Blood that can be used for the research of Liver Disease and Porphyria[1][2][3][4].

[Related Catalog]:

Research Areas >> Metabolic Disease

[In Vitro]

Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].

[References]

[1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720.

[2]. Zuijderhoudt FM, et al. On accuracy and precision of a HPLC method for measurement of urine porphyrin concentrations. Clin Chem Lab Med. 2000 Mar;38(3):227-30.

[3]. Hindmarsh JT, et al. Biochemical differentiation of the porphyrias. Clin Biochem. 1999 Nov;32(8):609-19.

[4]. MAGNUS IA, et al. Erythropoietic protoporphyria. A new porphyria syndrome with solar urticaria due to protoporphyrinaemia. Lancet. 1961 Aug 26;2(7200):448-51.