iodophenol

Names

[ CAS No. ]:
533-58-4

[ Name ]:
iodophenol

[Synonym ]:
ortho-iodophenol
2-Iodo-phenol
Phenol,o-iodo
o-iodo-pheno
EINECS 208-569-9
2-Iodbenzolol
MFCD00013963
o-Jodfenol
2-iodo-pheno
iodophenol
Phenol, 2-iodo-
1-iodo-2-hydroxybenzene
2-Jodfenol
2-lodophenol
o-iodophenol
2-Iodophenol
PHENOL,2-IODO

Chemical & Physical Properties

[ Density]:
2.0±0.1 g/cm3

[ Boiling Point ]:
187.2±13.0 °C at 760 mmHg

[ Melting Point ]:
37-40 °C(lit.)

[ Molecular Formula ]:
C₆H₅IO

[ Molecular Weight ]:
220.008

[ Flash Point ]:
67.0±19.8 °C

[ Exact Mass ]:
219.938507

[ PSA ]:
20.23000

[ LogP ]:
2.65

[ Vapour Pressure ]:
0.5±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.669

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
slightly soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SL5500000

CHEMICAL NAME :: Phenol, o-iodo-

CAS REGISTRY NUMBER :: 533-58-4

BEILSTEIN REFERENCE NO. :: 1855300

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C6-H5-I-O

MOLECULAR WEIGHT :: 220.01

WISWESSER LINE NOTATION :: QR BI

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4 gm/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness

REFERENCE :: RMSRA6 Revue Medicale de la Suisse Romande. (Societe Medicale de La Suisse Romande, 2 rue Bellefontaine, 1003 Lausanne, Switzerland) V.1- 1881- Volume(issue)/page/year: 16,449,1896

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H312 + H332-H315-H319-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
SL5500000

[ HS Code ]:
29081000

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2908199090

[ Summary ]:
HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0%

Articles

Regioselective synthesis of 1,3,5-substituted benzenes via the InCl(3)/2-iodophenol-catalyzed cyclotrimerization of alkynes.

J. Org. Chem. 76(20) , 8472-6, (2011)

A novel indium(III)-catalyzed cyclotrimerization of alkynes in the presence of 2-iodophenol gave 1,3,5-substituted benzenes in excellent yields with complete regioselectivity. The reaction condition i...

Study on Enhancement Principle and Stabilization for the Luminol-H2O2-HRP Chemiluminescence System.

PLoS ONE 10 , e0131193, (2015)

A luminol-H2O2-HRP chemiluminescence system with high relative luminescent intensity (RLU) and long stabilization time was investigated. First, the comparative study on the enhancement effect of ten c...

Highly efficient copper-catalyzed domino ring opening and Goldberg coupling cyclization for the synthesis of 3,4-dihydro-2H-1,4-benzoxazines.

Org. Lett. 11(9) , 1923-6, (2009)

trans-3,4-Dihydro-2H-1,4-benzoxazine moieties can be synthesized by domino aziridine ring opening with o-iodophenols followed by the copper-catalyzed Goldberg coupling cyclization (intramolecular C(ar...