1,4-Difluorobenzene

Names

[ CAS No. ]:
540-36-3

[ Name ]:
1,4-Difluorobenzene

[Synonym ]:
1,4-Difluorobenzene
2,5-difluorobenzene
Benzene, 1,4-difluoro-
FR DF BVR
p-Difluorobenzene
para-Difluorobenzene
MFCD00000344
Benzene,p-difluoro
EINECS 208-742-9
1.4-difluorobenzene
Benzene,1,4-difluoro

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
90.4±13.0 °C at 760 mmHg

[ Melting Point ]:
-13 °C

[ Molecular Formula ]:
C₆H₄F₂

[ Molecular Weight ]:
114.093

[ Flash Point ]:
2.2±0.0 °C

[ Exact Mass ]:
114.028107

[ LogP ]:
2.39

[ Vapour Pressure ]:
63.6±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.449

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CZ5658000

CHEMICAL NAME :: Benzene, p-difluoro-

CAS REGISTRY NUMBER :: 540-36-3

LAST UPDATED :: 199709

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C6-H4-F2

MOLECULAR WEIGHT :: 114.10

WISWESSER LINE NOTATION :: FR DF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 55 gm/m3/2H

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS

REFERENCE :: IZSBAI Izvestiya Sibirskogo Otdeleniya Akademii Nauk SSSR, Seriya Biologomeditsinskikh Nauk. (Novosibirsk, USSR) No.1-3, 1963-68. For publisher information, see ISBNBN. Volume(issue)/page/year: 3,91,1965

Safety Information

[ Symbol ]:

GHS02

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225

[ Precautionary Statements ]:
P210

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F:Flammable

[ Risk Phrases ]:
R11;R20

[ Safety Phrases ]:
S16-S29-S33-S7-S45-S36/37

[ RIDADR ]:
UN 1993 3/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
CZ5658000

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
29036990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2903999090

[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Prediction of convulsant activity of gases and vapors.

Eur. J. Med. Chem. 44 , 885-90, (2009)

The convulsant activity of 48 compounds studied by Eger et al. has been analyzed using an Abraham solvation equation. Four compounds identified by Eger et al. as more potent than expected were similar...