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Vinformide

Names

[ CAS No. ]:
54022-49-0

[ Name ]:
Vinformide

[Synonym ]:
Formyl-leurosine

Chemical & Physical Properties

[ Density]:
1.42g/cm3

[ Melting Point ]:
200-210ºC

[ Molecular Formula ]:
C₄₆H₅₄N₄O₁₀

[ Molecular Weight ]:
822.94200

[ Exact Mass ]:
822.38400

[ PSA ]:
163.47000

[ LogP ]:
4.11060

[ Index of Refraction ]:
1.684

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LR2962000

CHEMICAL NAME :: Formyl-leurosine

CAS REGISTRY NUMBER :: 54022-49-0

LAST UPDATED :: 198910

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C46-H54-N4-O10

MOLECULAR WEIGHT :: 823.04

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Human - man

DOSE/DURATION :: 500 ug/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Rodent - mouse Ascites tumor

DOSE/DURATION :: 10 mg/kg

REFERENCE :: EJCODS European Journal of Cancer and Clinical Oncology. (Pergamon Press, c/o Elsevier Science, 660 White Plains Rd., Tarrytown, NY 10591) V.17(7)- 25, 1981-89. For publisher information, see EJCAEL Volume(issue)/page/year: 19,1113,1983

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds