NSC-65381
Names
[ CAS No. ]:
543-21-5
[ Name ]:
NSC-65381
[Synonym ]:
Cellocidin
2-butynediamide
Lenamycin
Acetylene dicarboxamide
acetylene dicarboxylic diamide
but-2-ynediamide
Renamycin
acetylene dicarboxylic acid diamide
acetylenedicarboxamide
EINECS 200-816-9
Aquamycin
Acetylenedicarbonitrile
Chemical & Physical Properties
[ Density]:
1.41g/cm3
[ Boiling Point ]:
294ºC at 760 mmHg
[ Melting Point ]:
179ºC
[ Molecular Formula ]:
C4H4N2O2
[ Molecular Weight ]:
112.08700
[ Flash Point ]:
131.6ºC
[ Exact Mass ]:
112.02700
[ PSA ]:
86.18000
[ Appearance of Characters ]:
Fine Crystalline Powder | Cream to beige
[ Vapour Pressure ]:
0.00167mmHg at 25°C
[ Index of Refraction ]:
1.56
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AO9900000
- CHEMICAL NAME :
- Acetylenedicarboxamide
- CAS REGISTRY NUMBER :
- 543-21-5
- BEILSTEIN REFERENCE NO. :
- 1756134
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C4-H4-N2-O2
- MOLECULAR WEIGHT :
- 112.10
- WISWESSER LINE NOTATION :
- ZV1UU1VZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 89200 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (1),15,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 667 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (1),15,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 11 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JAJAAA Journal of Antibiotics, Series A. (Tokyo, Japan) V.6-20, 1953-67. For publisher information, see JANTAJ. Volume(issue)/page/year: 11,81,1958
Safety Information
[ Hazard Codes ]:
T
[ Risk Phrases ]:
25-21
[ Safety Phrases ]:
45-36/37-28A
[ HS Code ]:
2924199090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2924199090
[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%