1-(3-Chlorophenyl)-N-(2-hydroxyethyl)-5-methoxy-N-methyl-1H-pyrazole-3-carboxamide
Names
[ CAS No. ]:
54708-76-8
[ Name ]:
1-(3-Chlorophenyl)-N-(2-hydroxyethyl)-5-methoxy-N-methyl-1H-pyrazole-3-carboxamide
[Synonym ]:
pz-250
Chemical & Physical Properties
[ Density]:
1.31g/cm3
[ Boiling Point ]:
529ºC at 760 mmHg
[ Molecular Formula ]:
C14H16ClN3O3
[ Molecular Weight ]:
309.74800
[ Flash Point ]:
273.7ºC
[ Exact Mass ]:
309.08800
[ PSA ]:
67.59000
[ LogP ]:
1.59860
[ Index of Refraction ]:
1.595
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UQ6310000
- CHEMICAL NAME :
- 1H-Pyrazole-3-carboxamide, 1-(3-chlorophenyl)-N-(2-hydroxyethyl)-5-methoxy-N-met hyl-
- CAS REGISTRY NUMBER :
- 54708-76-8
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C14-H16-Cl-N3-O3
- MOLECULAR WEIGHT :
- 309.78
- WISWESSER LINE NOTATION :
- T5NNJ AR CG& CVN1&2Q EO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 460 mg/kg
- TOXIC EFFECTS :
- Behavioral - general anesthetic Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay)
- REFERENCE :
- JJPAAZ Japanese Journal of Pharmacology. (Japanese Pharmacological Soc., c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto 606, Japan) V.1- 1951- Volume(issue)/page/year: 25,781,1975