2H-1,24:12,15-Dietheno-6,10-metheno-16H-pyrido[2',3':17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinolin-9-ol,3,4,4a,5,16a,17,18,19-octahydro-21,22,26-trimethoxy-4,17-dimethyl-, (4aR,16aS)-
Names
[ CAS No. ]:
548-40-3
[ Name ]:
2H-1,24:12,15-Dietheno-6,10-metheno-16H-pyrido[2',3':17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinolin-9-ol,3,4,4a,5,16a,17,18,19-octahydro-21,22,26-trimethoxy-4,17-dimethyl-, (4aR,16aS)-
[Synonym ]:
Oxyacanthine
Oxyacanthin
vinetine
6,7,6'-trimethoxy-2,2'-dimethyl-oxyacanthan-12'-ol
6,6',7-Trimethoxy-2,2'-dimethyloxyacanthan-12'-ol
Oxyacanthan-12'-ol, 6,6',7'-trimethoxy-2,2'-dimethyl-
Oxycanthine
Chemical & Physical Properties
[ Density]:
1.204g/cm3
[ Boiling Point ]:
707ºC at 760mmHg
[ Molecular Formula ]:
C37H40N2O6
[ Molecular Weight ]:
608.72300
[ Flash Point ]:
381.4ºC
[ Exact Mass ]:
608.28900
[ PSA ]:
72.86000
[ LogP ]:
6.73520
[ Index of Refraction ]:
1.601
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RR6475000
- CHEMICAL NAME :
- Oxyacanthan-12'-ol, 6,6',7-trimethoxy-2,2'-dimethyl-
- CAS REGISTRY NUMBER :
- 548-40-3
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C37-H40-N2-O6
- MOLECULAR WEIGHT :
- 608.79
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,17,1953
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 24,2413,1976