3-Methyl-1-phenyl-4-(piperidinomethylene)-2-pyrazolin-5-one
Names
[ CAS No. ]:
5496-04-8
[ Name ]:
3-Methyl-1-phenyl-4-(piperidinomethylene)-2-pyrazolin-5-one
[Synonym ]:
5-methyl-2-phenyl-4-piperidin-1-ylmethylene-2,4-dihydro-pyrazol-3-one
5-Oxo-3-methyl-4-piperidinomethylen-1-phenyl-4,5-dihydro-pyrazol
AmbscPOD_15/0510
1-Phenyl-3-methyl-4-piperidinomethylenpyrazolon-5
3-Methyl-4-piperidinomethylen-1-phenyl-pyrazolon-(5)
2,4-dihydro-5-methyl-2-phenyl-4-(1-piperidinylmethylene)-3H-pyrazol-3-one
3-Methyl-1-phenyl-4-(piperidinomethylene)-2-pyrazolin-5-one
1-phenyl-3-methyl-4-piperidinomethylene-5-pyrazolone
2-Pyrazolin-5-one,3-methyl-1-phenyl-4-(piperidinomethylene)
Chemical & Physical Properties
[ Density]:
1.18g/cm3
[ Boiling Point ]:
375.5ºC at 760 mmHg
[ Molecular Formula ]:
C16H19N3O
[ Molecular Weight ]:
269.34200
[ Flash Point ]:
180.9ºC
[ Exact Mass ]:
269.15300
[ PSA ]:
35.91000
[ LogP ]:
2.21740
[ Index of Refraction ]:
1.623
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UQ9651000
- CHEMICAL NAME :
- 2-Pyrazolin-5-one, 3-methyl-1-phenyl-4-(piperidinomethylene)-
- CAS REGISTRY NUMBER :
- 5496-04-8
- BEILSTEIN REFERENCE NO. :
- 0616565
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C16-H19-N3-O
- MOLECULAR WEIGHT :
- 269.38
- WISWESSER LINE NOTATION :
- T6NTJ A1U- DT5NNVYJ BR& E1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CHTPBA Chimica Therapeutica. (Paris, France) V.1-8, 1965-73. For publisher information, see EJMCA5. Volume(issue)/page/year: 3,17,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CHTPBA Chimica Therapeutica. (Paris, France) V.1-8, 1965-73. For publisher information, see EJMCA5. Volume(issue)/page/year: 3,17,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - analgesia Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 19,1721,1969
Safety Information
[ HS Code ]:
2933990090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%