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4-Methylaminophenol sulfate

Names

[ CAS No. ]:
55-55-0

[ Name ]:
4-Methylaminophenol sulfate

[Synonym ]:
Phenol, 4-(methylamino)-, sulfate (1:1) (salt)
MFCD00013140
ARMOL
METOL4
GENOL
Phenol, p-methylamino-, sulfate (salt)
ELON
Metol sulphate
4-Methylamino-phenol,Sulfat
4-(Methylamino)phenol Sulfate
4-(methylamino)phenol sulphate
verol
METHOL
bis(4-hydroxy-N-methylanilinium) sulfate
pictol
p-Methylaminophenol Sulfate
photol
EINECS 200-237-1
4-(Methylamino)phenol sulfate (1:1)
p-Methylaminophenol sulfate (VAN)
4-Methylaminophenol sulfate
Motol

Chemical & Physical Properties

[ Density]:
1.577

[ Boiling Point ]:
262.7ºC at 760 mmHg

[ Melting Point ]:
260 °C (dec.)(lit.)

[ Molecular Formula ]:
C7H11NO5S

[ Molecular Weight ]:
221.231

[ Flash Point ]:
148.6ºC

[ Exact Mass ]:
221.035797

[ PSA ]:
115.24000

[ LogP ]:
1.93490

[ Storage condition ]:
−20°C

[ Stability ]:
Stability Combustible. Incompatible with strong oxidizing agents, acids, acid halides.

[ Water Solubility ]:
50 g/L (20 ºC)

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SL8650000
CHEMICAL NAME :
Phenol, p-methylamino-, sulfate (salt)
CAS REGISTRY NUMBER :
55-55-0
LAST UPDATED :
199710
DATA ITEMS CITED :
17
MOLECULAR FORMULA :
C7-H9-N-O.1/2H2-O4-S
MOLECULAR WEIGHT :
219.23
WISWESSER LINE NOTATION :
QR DM1 &S-O4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
705 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
565 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - tremor Kidney, Ureter, Bladder - other changes in urine composition
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
769 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
1585 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
9350 mg/kg/11D-C
TOXIC EFFECTS :
Endocrine - changes in spleen weight Blood - changes in spleen
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
6600 mg/kg/94D-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Endocrine - changes in spleen weight Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4300 mg/kg/61D-I
TOXIC EFFECTS :
Blood - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
167 ug/plate
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 9(Suppl 9),1,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81914 No. of Facilities: 9601 (estimated) No. of Industries: 85 No. of Occupations: 47 No. of Employees: 40485 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81914 No. of Facilities: 6348 (estimated) No. of Industries: 37 No. of Occupations: 34 No. of Employees: 43146 (estimated) No. of Female Employees: 24720 (estimated)

Safety Information

[ Symbol ]:

GHS07, GHS08, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H317-H373-H410

[ Precautionary Statements ]:
P260-P280-P301 + P312 + P330

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;N:Dangerousfortheenvironment;

[ Risk Phrases ]:
R22;R43;R48/22;R50/53

[ Safety Phrases ]:
S36/37-S46-S60-S61

[ RIDADR ]:
UN 3077 9/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
SL8650000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
29222900

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 29222900

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