4-Methylaminophenol sulfate
Names
[ CAS No. ]:
55-55-0
[ Name ]:
4-Methylaminophenol sulfate
[Synonym ]:
Phenol, 4-(methylamino)-, sulfate (1:1) (salt)
MFCD00013140
ARMOL
METOL4
GENOL
Phenol, p-methylamino-, sulfate (salt)
ELON
Metol sulphate
4-Methylamino-phenol,Sulfat
4-(Methylamino)phenol Sulfate
4-(methylamino)phenol sulphate
verol
METHOL
bis(4-hydroxy-N-methylanilinium) sulfate
pictol
p-Methylaminophenol Sulfate
photol
EINECS 200-237-1
4-(Methylamino)phenol sulfate (1:1)
p-Methylaminophenol sulfate (VAN)
4-Methylaminophenol sulfate
Motol
Chemical & Physical Properties
[ Density]:
1.577
[ Boiling Point ]:
262.7ºC at 760 mmHg
[ Melting Point ]:
260 °C (dec.)(lit.)
[ Molecular Formula ]:
C7H11NO5S
[ Molecular Weight ]:
221.231
[ Flash Point ]:
148.6ºC
[ Exact Mass ]:
221.035797
[ PSA ]:
115.24000
[ LogP ]:
1.93490
[ Storage condition ]:
−20°C
[ Stability ]:
Stability Combustible. Incompatible with strong oxidizing agents, acids, acid halides.
[ Water Solubility ]:
50 g/L (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SL8650000
- CHEMICAL NAME :
- Phenol, p-methylamino-, sulfate (salt)
- CAS REGISTRY NUMBER :
- 55-55-0
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 17
- MOLECULAR FORMULA :
- C7-H9-N-O.1/2H2-O4-S
- MOLECULAR WEIGHT :
- 219.23
- WISWESSER LINE NOTATION :
- QR DM1 &S-O4
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 705 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 565 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor Kidney, Ureter, Bladder - other changes in urine composition
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 769 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 1585 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 9350 mg/kg/11D-C
- TOXIC EFFECTS :
- Endocrine - changes in spleen weight Blood - changes in spleen
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 6600 mg/kg/94D-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Endocrine - changes in spleen weight Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4300 mg/kg/61D-I
- TOXIC EFFECTS :
- Blood - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 167 ug/plate
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 9(Suppl 9),1,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81914 No. of Facilities: 9601 (estimated) No. of Industries: 85 No. of Occupations: 47 No. of Employees: 40485 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81914 No. of Facilities: 6348 (estimated) No. of Industries: 37 No. of Occupations: 34 No. of Employees: 43146 (estimated) No. of Female Employees: 24720 (estimated)
Safety Information
[ Symbol ]:
GHS07, GHS08, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H317-H373-H410
[ Precautionary Statements ]:
P260-P280-P301 + P312 + P330
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xn:Harmful;N:Dangerousfortheenvironment;
[ Risk Phrases ]:
R22;R43;R48/22;R50/53
[ Safety Phrases ]:
S36/37-S46-S60-S61
[ RIDADR ]:
UN 3077 9/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
SL8650000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
[ HS Code ]:
29222900
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 29222900
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