2,6-Difluoroaniline

Names

[ Name ]:
2,6-Difluoroaniline

[Synonym ]:
2,6-DIFLUOROBENZENAMINE
MFCD00007655
2,6-Difluoroaniline
6-Difluoroaniline
EINECS 226-853-0
2,6-Difuluorobenzenamine
2,6-difluoro-aniline
2,6-Difuluoroaniline
Benzenamine, 2,6-difluoro-
2,6-DifluorophenylaMine
2,6-DifluorobenzeneaMine
2,5-DIFLUORO-3-NITROBENZOPHENONE

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
154.0±0.0 °C at 760 mmHg

[ Melting Point ]:
144-148ºC

[ Molecular Formula ]:
C₆H₅F₂N

[ Molecular Weight ]:
129.107

[ Flash Point ]:
43.3±0.0 °C

[ Exact Mass ]:
129.039001

[ PSA ]:
26.02000

[ LogP ]:
1.65

[ Vapour Pressure ]:
3.2±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.521

[ Storage condition ]:
Flammables area

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226-H302 + H312 + H332-H317

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R10;R20/21/22;R36/37/38

[ Safety Phrases ]:
S36-S36/37/39-S26-S23-S16-S16/23/26/36/37/39

[ RIDADR ]:
UN 1993 3/PG 3

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
2942000000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2921420090

[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Design and synthesis of N-2,6-difluorophenyl-5-methoxyl-1,2,4-triazolo[1,5-a]-pyrimidine-2-sulfonamide as acetohydroxyacid synthase inhibitor.

Bioorg. Med. Chem. 17(8) , 3011-7, (2009)

Triazolopyrimidine-2-sulfonamide belongs to a herbicide group called acetohydroxyacid synthase inhibitors. With the aim to discover new triazolopyrimidine sulfonanilide compounds with high herbicidal ...

N-Phenyl-N-purin-6-yl ureas: the design and synthesis of p38alpha MAP kinase inhibitors.

Bioorg. Med. Chem. Lett. 13(6) , 1191-4, (2003)

The design, synthesis and SAR of a series of 2,6,9-trisubstituted purine inhibitors of p38alpha kinase is reported. Synthetic routes were devised to allow for array synthesis in which all three points...

Catalyzed double Michael addition of anilines to vinyl sulfone. Chen JJ, et al.

Tetrahedron Lett. 44(17) , 3459-62, (2003)