Prostaglandin F2α 1,15-lactone (PGF2α 1,15-lactone)
Names
[ CAS No. ]:
55314-49-3
[ Name ]:
Prostaglandin F2α 1,15-lactone (PGF2α 1,15-lactone)
[Synonym ]:
pgf2-alpha1,15-lactone
Prosta-5,13-dien-1-one, 1,15-epoxy-9,11-dihydroxy-, (5Z,9α,11α,13E,15S)-
(5Z,9α,11α,13E,15S)-9,11-Dihydroxy-1,15-epoxyprosta-5,13-dien-1-one
13e,15s)-1-alph
PROSTAGLANDIN F2ALPHA 1,15-LACTONE
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
524.1±50.0 °C at 760 mmHg
[ Molecular Formula ]:
C20H32O4
[ Molecular Weight ]:
336.466
[ Flash Point ]:
180.9±23.6 °C
[ Exact Mass ]:
336.230072
[ PSA ]:
66.76000
[ LogP ]:
3.09
[ Vapour Pressure ]:
0.0±3.1 mmHg at 25°C
[ Index of Refraction ]:
1.503
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UK8020600
- CHEMICAL NAME :
- Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, lambda-lactone, (5Z,9-alpha,11-alpha, 13E,15S)-
- CAS REGISTRY NUMBER :
- 55314-49-3
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C20-H32-O4
- MOLECULAR WEIGHT :
- 336.52
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- DOSE :
- 4 mg/kg
- SEX/DURATION :
- female 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - menstrual cycle changes or disorders
- REFERENCE :
- PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022) V.1- 1972- Volume(issue)/page/year: 14,477,1977
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 800 ug/kg
- SEX/DURATION :
- female 4 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 26,1089,1983