6-hydrazinyl-4-methyl-7H-pyrimido[4,5-b][1,4]thiazin-2-amine
Names
[ CAS No. ]:
55383-66-9
[ Name ]:
6-hydrazinyl-4-methyl-7H-pyrimido[4,5-b][1,4]thiazin-2-amine
Chemical & Physical Properties
[ Molecular Formula ]:
C7H10N6S
[ Molecular Weight ]:
210.25900
[ Exact Mass ]:
210.06900
[ PSA ]:
128.24000
[ LogP ]:
0.42310
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UW7863000
- CHEMICAL NAME :
- 7H-Pyrimido(4,5-b)(1,4)thiazine, 2-amino-6-hydrazino-4-methyl-
- CAS REGISTRY NUMBER :
- 55383-66-9
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C7-H10-N6-S
- MOLECULAR WEIGHT :
- 210.29
- WISWESSER LINE NOTATION :
- T66 BN DN GN JS IHJ CZ E1 HMZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- REFERENCE :
- PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 11,1205,1977