H-Gly-Gly-OH

Names

[ CAS No. ]:
556-50-3

[ Name ]:
H-Gly-Gly-OH

[Synonym ]:
2-(2-AMINOTHIAZOL-4-YL) GLYOXYLIC ACID
(2-amino-thiazol-4-yl)-oxo-acetic acid
ATGA:2-(2-AMINOTHIAZOL-4-YL) GLYOXYLIC ACID
Glycyl-glycine
Glycine, glycyl-
2-(2-Aminothiazol-4-yl)-2-oxoacetic acid
N-Glycylglycine
Glycylglycine
H-Gly-Gly-OH
glycine anhydride
2-(2-ammonioacetamido)acetate
(2-aminothiazol-4-yl)glyoxylic acid
ATGA
Diglycocoll
H2N-Gly-Gly-OH
diglycine
MFCD00008130
(2-amino-4-thiazolyl)glyoxylic acid
EINECS 209-127-8
2-(2-aminothiazol-4-yl)glyoxylic Acid (ATGA)
2-oxo-2-(2-aminothiazol-4-yl)acetic acid
glycine dipeptide
Gly-gly

Biological Activity

[Description]:

Glycylglycine is the simplest of all peptides and could function as a gamma-glutamyl acceptor.

[Related Catalog]:

Research Areas >> Metabolic Disease

Natural Products >> Others

[Target]

Human Endogenous Metabolite

[References]

[1]. Glycylglycine

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
453.2±30.0 °C at 760 mmHg

[ Melting Point ]:
220-240 °C (dec.)

[ Molecular Formula ]:
C₄H₈N₂O₃

[ Molecular Weight ]:
132.118

[ Flash Point ]:
227.9±24.6 °C

[ Exact Mass ]:
132.053497

[ PSA ]:
92.42000

[ LogP ]:
-1.85

[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C

[ Index of Refraction ]:
1.505

[ Storage condition ]:
-15°C

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
SOLUBLE IN HOT WATER

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36

[ Safety Phrases ]:
S24/25-S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Abiogenic Syntheses of Lipoamino Acids and Lipopeptides and their Prebiotic Significance.

Orig. Life Evol. Biosph. 45 , 427-37, (2015)

Researchers have formed peptide bonds under a variety of presumed prebiotic conditions. Here it is proposed that these same conditions would have also formed amide bonds between fatty acids and amino ...

Recurrence of carbamoyl phosphate synthetase 1 (CPS1) deficiency in Turkish patients: characterization of a founder mutation by use of recombinant CPS1 from insect cells expression.

Mol. Genet. Metab. 113(4) , 267-73, (2014)

Carbamoyl phosphate synthetase 1 (CPS1) deficiency due to CPS1 mutations is a rare autosomal-recessive urea cycle disorder causing hyperammonemia that can lead to death or severe neurological impairme...

Inhibition of calcium-calmodulin complex formation by vasorelaxant basic dipeptides demonstrated by in vitro and in silico analyses.

Biochim. Biophys. Acta 1840(10) , 3073-8, (2014)

Tryptophan-histidine (Trp-His) was found to suppress the activity of the Ca²⁺/calmodulin (CaM)-dependent protein kinases II (CaMKII), which requires the Ca²⁺-CaM complex for an initial activation. In ...