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3-Methylcholanthrene

Names

[ CAS No. ]:
56-49-5

[ Name ]:
3-Methylcholanthrene

[Synonym ]:
MFCD00003704
3-Methylcholanthrene
EINECS 200-276-4
3-Methyl-1,2-dihydrocyclopenta[ij]tetraphene
3-methyl-1,2-dihydrobenzo[j]aceanthrylene
Benz[j]aceanthrylene, 1,2-dihydro-3-methyl-

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
506.4±30.0 °C at 760 mmHg

[ Melting Point ]:
178-180ºC

[ Molecular Formula ]:
C21H16

[ Molecular Weight ]:
268.352

[ Flash Point ]:
253.2±18.7 °C

[ Exact Mass ]:
268.125214

[ LogP ]:
7.11

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.781

[ Storage condition ]:
2-8°C

[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents.

MSDS

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H350-H413

[ Precautionary Statements ]:
P201-P308 + P313

[ Personal Protective Equipment ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
T,Xn,F

[ Risk Phrases ]:
R45

[ Safety Phrases ]:
53-36/37/39-45-36-26-16-36/37

[ RIDADR ]:
UN 2811

[ WGK Germany ]:
3

[ RTECS ]:
FZ3675000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2902909090

Precursor & DownStream

Customs

[ HS Code ]: 2902909090

[ Summary ]:
2902909090 other aromatic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

Articles

Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

J. Sci. Ind. Res. 65(10) , 808, (2006)

Drug-induced liver injury (DILI) is a significant concern in drug development due to the poor concordance between preclinical and clinical findings of liver toxicity. We hypothesized that the DILI typ...

Developing structure-activity relationships for the prediction of hepatotoxicity.

Chem. Res. Toxicol. 23 , 1215-22, (2010)

Drug-induced liver injury is a major issue of concern and has led to the withdrawal of a significant number of marketed drugs. An understanding of structure-activity relationships (SARs) of chemicals ...

HepG2 cells as an in vitro model for evaluation of cytochrome P450 induction by xenobiotics.

Arch. Pharm. Res. 38 , 691-704, (2015)

Although various in vitro assays have been developed to evaluate the cytochrome P450 (CYP)-inducing potential of drug candidates, there is a continuing need for the development of a reliable model in ...


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Related Compounds