cis-1-(2-Chloroethyl)-3-(3-hydroxycyclohexyl)-1-nitrosourea
Names
[ CAS No. ]:
56323-45-6
[ Name ]:
cis-1-(2-Chloroethyl)-3-(3-hydroxycyclohexyl)-1-nitrosourea
[Synonym ]:
cis-3-OH CCNU
cis-3-Hydroxy CCNU
Chemical & Physical Properties
[ Density]:
1.46g/cm3
[ Molecular Formula ]:
C9H16ClN3O3
[ Molecular Weight ]:
249.69500
[ Exact Mass ]:
249.08800
[ PSA ]:
82.00000
[ LogP ]:
1.61260
[ Index of Refraction ]:
1.605
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YS4982850
- CHEMICAL NAME :
- Urea, 1-(2-chloroethyl)-3-(3-hydroxycyclohexyl)-1-nitroso-, (Z)-
- CAS REGISTRY NUMBER :
- 56323-45-6
- LAST UPDATED :
- 198609
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C9-H16-Cl-N3-O3
- MOLECULAR WEIGHT :
- 249.73
- WISWESSER LINE NOTATION :
- L6TJ AQ CMVNNO&2G -C
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD10 - Lethal Dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,1095,1980