Dimethyl(2-methyl-2-propanyl)silanecarbonitrile

Names

[ Name ]:
Dimethyl(2-methyl-2-propanyl)silanecarbonitrile

[Synonym ]:
Dimethyl(2-methyl-2-propanyl)silanecarbonitrile
t-Bu(Me)2SiCN
MFCD00054923
tert-Butyl-cyano-dimethylsilane
tert-Butyldimethylsilyl cyanide
Silanecarbonitrile, 1-(1,1-dimethylethyl)-1,1-dimethyl-
tert-butyldimethylsilylnitrile

Chemical & Physical Properties

[ Density]:
0.8±0.1 g/cm3

[ Boiling Point ]:
166.4±9.0 °C at 760 mmHg

[ Melting Point ]:
76-79ºC(lit.)

[ Molecular Formula ]:
C₇H₁₅NSi

[ Molecular Weight ]:
141.286

[ Flash Point ]:
54.5±18.7 °C

[ Exact Mass ]:
141.097382

[ PSA ]:
23.79000

[ LogP ]:
2.23

[ Vapour Pressure ]:
1.8±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.412

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H311-H331

[ Precautionary Statements ]:
P261-P280-P301 + P310-P311

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T

[ Risk Phrases ]:
R23/24/25

[ Safety Phrases ]:
36/37/39-45

[ RIDADR ]:
UN 2811 6.1/PG 1

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

Synthetic Route

Click to get detail synthetic route

Articles

Stereocontrolled access to orthogonally protected anti,anti-4-aminopiperidine-3,5-diols through chemoselective reduction of enantiopure beta-lactam cyanohydrins.

J. Org. Chem. 72(21) , 7980-91, (2007)

The cyanosilylation of enantiopure 4-oxoazetidine-2-carbaldehydes with tert-butyldimethylsilyl cyanide was promoted by either molecular sieves or catalytic amount of sodium carbonate to give O-silylat...

J. Org. Chem. 51 , 5010, (1986)

Addition of tert-butyldimethyl-or tert-butyldiphenylsilyl cyanide to hindered ketones. Golinski M, et al.

J. Org. Chem. 58(1) , 159-64, (1993)