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Vildagliptin carboxylic acid metabolite (trifluoroacetate salt)

Names

[ CAS No. ]:
565453-41-0

[ Name ]:
Vildagliptin carboxylic acid metabolite (trifluoroacetate salt)

[Synonym ]:
L-Proline, N-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)glycyl-, compd. with 2,2,2-trifluoroacetic acid (1:1)
N-[(1r,3r)-3-Hydroxyadamantan-1-yl]glycyl-L-proline trifluoroacetate (1:1)

Biological Activity

[Description]:

Vildagliptin carboxylic acid metabolite (M20.7) TFA is a potent P450 enzyme activity inhibitor[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450
Research Areas >> Metabolic Disease

[References]

[1]. He H, et al. Absorption, metabolism, and excretion of [14C]vildagliptin, a novel dipeptidyl peptidase 4 inhibitor, in humans. Drug Metab Dispos. 2009 Mar;37(3):536-44.  

Chemical & Physical Properties

[ Molecular Formula ]:
C19H27F3N2O6

[ Molecular Weight ]:
436.42

[ Exact Mass ]:
436.182129

Related Compounds