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16α-Hydroxyestrone

Names

[ CAS No. ]:
566-76-7

[ Name ]:
16α-Hydroxyestrone

[Synonym ]:
3,16-Dihydroxyestra-1(10),2,4-trien-17-one
Estra-1,3,5(10)-triene-3,16a-diol-17-one
Estra-1(10),2,4-trien-17-one, 3,16-dihydroxy-, (16α)-
Estra-1,3,5(10)-trien-17-one, 3,16α-dihydroxy-
(16α)-3,16-Dihydroxyestra-1(10),2,4-trien-17-one
1,3,5[10]-ESTRATRIENE-3,16ALPHA-DIOL-17-ONE
3,16-Dihydroxyestra-1,3,5(10)-trien-17-one
Estra-1(10),2,4-trien-17-one, 3,16-dihydroxy-
3,16a-dihydroxy-Estra-1,3,5(10)-trien-17-one
estra-1,3,5(10)-trien-17-one, 3,16-dihydroxy-, (16α)-
16ALPHA-HYDROXYESTERONE
16α-Hydroxy Estrone
16alpha-hydroxyestrone
16Alpha-Hydroxy Estrone
3,16-dihydroxy-Estra-1,3,5(10)-trien-17-one
3,16α-Dihydroxyestra-1,3,5(10)-trien-17-one
Estra-1,3,5(10)-trien-17-one, 3,16-dihydroxy-
16A-hydroxyestrone

Biological Activity

[Description]:

16α-Hydroxyestrone (16αOHE) is a major Estradiol metabolite. 16α-Hydroxyestrone (16αOHE) can be used for the research of metabolic disease[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[In Vitro]

Increasing levels of active estrogen metabolites, 16α-Hydroxyestrone and E3, are associated with increasing bone mineral densit[1].

[References]

[1]. Napoli N, et al , Armamento-Villareal R. Estrogen metabolism modulates bone density in men. Calcif Tissue Int. 2007;80(4):227-232.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
493.2±45.0 °C at 760 mmHg

[ Melting Point ]:
209-211ºC

[ Molecular Formula ]:
C18H22O3

[ Molecular Weight ]:
286.366

[ Flash Point ]:
266.2±25.2 °C

[ Exact Mass ]:
286.156891

[ PSA ]:
57.53000

[ LogP ]:
2.32

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.612

Safety Information

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R40

[ Safety Phrases ]:
S22-S36

Precursor & DownStream

Precursor

DownStream

Related Compounds