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9H-Purin-6-amine,N-hydroxy-

Names

[ CAS No. ]:
5667-20-9

[ Name ]:
9H-Purin-6-amine,N-hydroxy-

[Synonym ]:
N-Hydroxy-1H-purin-6-amine
6-N-Hydroxylaminopurine
6-Hydroxylaminopurine
6-Hydroxylamin purin
EINECS 227-125-5
6-Hydroxyaminopurine
6-Hydroxylamino-purin
N-Hydroxyadenine
HAP (VAN)
ADENINE,N-HYDROXY
N6-hydroxy-9H-purin-6-amine
N-Hydroxy-1H-adenine
N-(7H-purin-6-yl)hydroxylamine
6-N-Hydroxyaminopurine
N(6)-hydroxyadenine
N-(9H-purin-6-yl)-hydroxylamine

Chemical & Physical Properties

[ Density]:
1.96g/cm3

[ Boiling Point ]:
333.3ºC at 760 mmHg

[ Molecular Formula ]:
C5H5N5O

[ Molecular Weight ]:
151.12600

[ Flash Point ]:
155.4ºC

[ Exact Mass ]:
151.04900

[ PSA ]:
86.72000

[ LogP ]:
0.22700

[ Index of Refraction ]:
1.932

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AU6300000
CHEMICAL NAME :
Adenine, N-hydroxy-
CAS REGISTRY NUMBER :
5667-20-9
LAST UPDATED :
199410
DATA ITEMS CITED :
15
MOLECULAR FORMULA :
C5-H5-N5-O
MOLECULAR WEIGHT :
151.15
WISWESSER LINE NOTATION :
T56 BM DN FN HNJ IMQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
470 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
400 mg/kg
SEX/DURATION :
female 11 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Specific Developmental Abnormalities - urogenital system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
400 mg/kg
SEX/DURATION :
female 11 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death

MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells
TEST SYSTEM :
Rodent - hamster Embryo
DOSE/DURATION :
5 mg/L
REFERENCE :
PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- Volume(issue)/page/year: 78,5685,1981

Safety Information

[ Hazard Codes ]:
Xn

Synthetic Route

Precursor & DownStream

Precursor

DownStream


Related Compounds