1,4-bis(chloromethoxymethyl)benzene
Names
[ CAS No. ]:
56894-91-8
[ Name ]:
1,4-bis(chloromethoxymethyl)benzene
Chemical & Physical Properties
[ Density]:
1.233g/cm3
[ Boiling Point ]:
307.1ºC at 760 mmHg
[ Molecular Formula ]:
C10H12Cl2O2
[ Molecular Weight ]:
235.10700
[ Flash Point ]:
114.4ºC
[ Exact Mass ]:
234.02100
[ PSA ]:
18.46000
[ LogP ]:
3.11240
[ Index of Refraction ]:
1.526
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CY8420000
- CHEMICAL NAME :
- Benzene, 1,4-bis(chloromethoxymethyl)-
- CAS REGISTRY NUMBER :
- 56894-91-8
- LAST UPDATED :
- 199510
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C10-H12-Cl2-O2
- MOLECULAR WEIGHT :
- 235.12
- WISWESSER LINE NOTATION :
- G1O1R D1O1G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2590 mg/kg/72W-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,2553,1975
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 310 mg/kg/78W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,2553,1975
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 970 mg/kg/81W-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,2553,1975 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,37,1977 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,37,1977 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987