3,5-Dichloro-4-Aminobenzoic acid

Names

[ Name ]:
3,5-Dichloro-4-Aminobenzoic acid

[Synonym ]:
3,5-Dichloro-4-Aminobenzoic acid
4-amino-3,5-dichlorobenzoate
NAB-930
Benzoic acid,4-amino-3,5-dichloro
Benzoic acid, 4-amino-3,5-dichloro-
3.5-Dichlor-4-amino-benzoesaeure
MFCD00017091
4-AMINO-3,5-DICHLOROBENZOIC ACID
EINECS 260-468-9
4-Amino-3,5-dichlor-benzoesaeure
4-amino-3,5-dichloro-benzoic acid

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
344.2±42.0 °C at 760 mmHg

[ Melting Point ]:
290-293 °C(lit.)

[ Molecular Formula ]:
C₇H₅Cl₂NO₂

[ Molecular Weight ]:
206.026

[ Flash Point ]:
162.0±27.9 °C

[ Exact Mass ]:
204.969727

[ PSA ]:
63.32000

[ LogP ]:
3.62

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.658

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DG1930000

CHEMICAL NAME :: Benzoic acid, 4-amino-3,5-dichloro-

CAS REGISTRY NUMBER :: 56961-25-2

BEILSTEIN REFERENCE NO. :: 2805751

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C7-H5-Cl2-N-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4618 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - respiratory depression Gastrointestinal - ulceration or bleeding from small intestine Gastrointestinal - hypermotility, diarrhea

REFERENCE :: IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 15,741,1984

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi,Xn

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
DG1930000

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

Mutagenicity and DNA-damaging potential of clenbuterol and its metabolite 4-amino-3,5-dichlorobenzoic acid in vitro.

Food Chem. Toxicol. 77 , 82-92, (2015)

The aim of this study was to evaluate in vitro toxicity of clenbuterol and its metabolite 4-amino-3,5-dichlorobenzoic acid. Cytotoxicity and pro-oxidative effect of both compounds were studied on huma...