Carpachromene

Names

[ Name ]:
Carpachromene

[Synonym ]:
Carpachromene
2H,6H-Benzo[1,2-b:5,4-b']dipyran-6-one, 5-hydroxy-8-(4-hydroxyphenyl)-2,2-dimethyl-
Carpachromen
Flemichin B
2S-Lupinifolin
5-Hydroxy-8-(4-hydroxyphenyl)-2,2-dimethyl-2H,6H-pyrano[3,2-g]chromen-6-one

Biological Activity

[Description]:

Carpachromene is a potent α-glucosidase enzyme inhibitor. Carpachromene ameliorates insulin resistance in HepG2 cells via modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 pathway[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Alaaeldin R, et al. Carpachromene Ameliorates Insulin Resistance in HepG2 Cells via Modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 Pathway. Molecules. 2021 Dec 16;26(24):7629.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
562.1±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₁₆O₅

[ Molecular Weight ]:
336.34

[ Flash Point ]:
205.8±23.6 °C

[ Exact Mass ]:
336.099762

[ PSA ]:
79.90000

[ LogP ]:
4.60

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.660

[ Storage condition ]:
?20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H410

[ Precautionary Statements ]:
P273-P501

[ Hazard Codes ]:
N

[ Risk Phrases ]:
50

[ Safety Phrases ]:
S61

[ RIDADR ]:
UN 3077 9 / PGIII

[ Hazard Class ]:
50