1,2,10-Trihydroxyanthracene

Names

[ CAS No. ]:
577-33-3

[ Name ]:
1,2,10-Trihydroxyanthracene

[Synonym ]:
MFCD00001251
Leucoalizarin
1,2,10-Trihydroxyanthracene
anthracene-1,2,10-triol
Leukoalizarin
Anthrarobin
3,4,9-Trihydroxyanthracene
EINECS 209-410-6
Desoxyalizarin
1,2,10-Anthratriol
3,4-Dihydroxyanthranol

Biological Activity

[Description]:

Anthrarobin is an antipsoriatic agent with antibacterial and oxidative potential.

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

Chemical & Physical Properties

[ Density]:
1.479g/cm3

[ Boiling Point ]:
528ºC at 760 mmHg

[ Melting Point ]:
218ºC (dec.)(lit.)

[ Molecular Formula ]:
C₁₄H₁₀O₃

[ Molecular Weight ]:
226.23

[ Flash Point ]:
267ºC

[ Exact Mass ]:
226.06300

[ PSA ]:
60.69000

[ LogP ]:
3.10980

[ Index of Refraction ]:
1.837

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CB1220000

CHEMICAL NAME :: 1,2,10-Anthracenetriol

CAS REGISTRY NUMBER :: 577-33-3

BEILSTEIN REFERENCE NO. :: 3531675

LAST UPDATED :: 199709

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C14-H10-O3

MOLECULAR WEIGHT :: 226.24

WISWESSER LINE NOTATION :: L C666J BQ FQ GQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 100 ug/plate

REFERENCE :: BCSTB5 Biochemical Society Transactions. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1973- Volume(issue)/page/year: 5,1489,1977

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
CB1220000

Precursor & DownStream

Precursor

DownStream

Articles

Structure specificity of the antipsoriatic anthrones.

Br. J. Dermatol. 105 Suppl 20 , 6-11, (1981)

In the investigations of Krebs and Schaltegger between 1964 and 1972 on the structure specificity of the antipsoriatic anthrones it could be shown that at least a 1-hydroxy-9-anthrone is necessary for...

Allergic contact dermatitis from anthrarobin.

Contact Dermatitis 33(5) , 361, (1995)