5-Hydroxyquinoline

Names

[ CAS No. ]:
578-67-6

[ Name ]:
5-Hydroxyquinoline

[Synonym ]:
isoquinolin-5-ol
5-Isoquinolinol
MFCD00006792
5-Quinolinol
quinolin-5-ol
1H-Quinolin-5-one
Chinolin-5-ol
5-Hydroxyquinoline
5-hydroxy-quinoline
EINECS 209-428-4

Biological Activity

[Description]:

5-Hydroxyquinoline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
313.0±15.0 °C at 760 mmHg

[ Melting Point ]:
223-226 °C(lit.)

[ Molecular Formula ]:
C₉H₇NO

[ Molecular Weight ]:
145.158

[ Flash Point ]:
143.1±20.4 °C

[ Exact Mass ]:
145.052765

[ PSA ]:
33.12000

[ LogP ]:
1.45

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.691

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VC4100000

CHEMICAL NAME :: 5-Quinolinol

CAS REGISTRY NUMBER :: 578-67-6

BEILSTEIN REFERENCE NO. :: 0114514

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H7-N-O

MOLECULAR WEIGHT :: 145.17

WISWESSER LINE NOTATION :: T66 BNJ GQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 100 ug/plate

REFERENCE :: JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 60,405,1978

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
VC4100000

[ HS Code ]:
2933499090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.

Bioorg. Med. Chem. Lett. 20 , 69-73, (2010)

A multiple linear regression QSAR model was developed based on a set of 61 compounds with internally consistent permeability data measured across Franz cell. The data was normalized using a mean perme...

Infrared Spectrum and UV-Induced Photochemistry of Matrix-Isolated 5-Hydroxyquinoline.

J. Phys. Chem. A 119 , 6296-308, (2015)

The structure, infrared spectrum, and photochemistry of 5-hydroxyquinoline (5HQ) were studied by matrix isolation infrared spectroscopy, complemented by theoretical calculations performed at the DFT(B...

Analysis of morphine in serum by high performance liquid chromatography with amperometric detection.

Ther. Drug Monit. 4(3) , 307-14, (1982)

In this report we describe a rapid and sensitive micromethod using high performance liquid chromatography (HPLC) with electrochemical detection (ED) to measure morphine concentration in serum or plasm...