5-METHYLCYTOSINE HYDROCHLORIDE
Names
[ CAS No. ]:
58366-64-6
[ Name ]:
5-METHYLCYTOSINE HYDROCHLORIDE
[Synonym ]:
2(1H)-pyrimidinone, 4-amino-5-methyl-, hydrochloride (1:1)
4-Amino-5-methylpyrimidin-2(1H)-one hydrochloride (1:1)
EINECS 261-223-9
2(1H)-pyrimidinone, 3,4-dihydro-4-imino-5-methyl-, hydrochloride (1:1)
6-Amino-5-methylpyrimidin-2(1H)-onhydrochlorid(1:1)
2(1H)-Pyrimidinone, 6-amino-5-methyl-, hydrochloride (1:1)
6-amino-5-methylpyrimidin-2(1H)-one hydrochloride (1:1)
4-Imino-5-methyl-3,4-dihydropyrimidin-2(1H)-one hydrochloride (1:1)
MFCD00035313
6-amino-5-methyl-1H-pyrimidin-2-one,hydrochloride
6-Amino-5-methyl-2(1H)-pyrimidinone hydrochloride (1:1)
Chemical & Physical Properties
[ Melting Point ]:
293-295°C effervescence
[ Molecular Formula ]:
C5H8ClN3O
[ Molecular Weight ]:
161.589
[ Exact Mass ]:
161.035583
[ PSA ]:
72.03000
[ LogP ]:
1.45600
[ Storage condition ]:
Store at RT.
[ Stability ]:
This compound looses chloride readily. Keep container tightly closed, and store in freezer.
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
Articles
Eur. J. Mass Spectrom. (Chichester, Eng.) 20(6) , 467-75, (2015)
This paper describes non-covalent complexes between zwitterionic 3-(1-alkyl-3N-imidazolio)- propane-1-sulfonates and different amines. Electrospray ionization (ESI) mass spectrometry and collision- in...
Crystal structure of TET2-DNA complex: insight into TET-mediated 5mC oxidation.Cell 155(7) , 1545-55, (2013)
TET proteins oxidize 5-methylcytosine (5mC) on DNA and play important roles in various biological processes. Mutations of TET2 are frequently observed in myeloid malignance. Here, we present the cryst...
3-D DNA methylation phenotypes correlate with cytotoxicity levels in prostate and liver cancer cell models.BMC Pharmacol. Toxicol. 14 , 11, (2013)
The spatial organization of the genome is being evaluated as a novel indicator of toxicity in conjunction with drug-induced global DNA hypomethylation and concurrent chromatin reorganization. 3D quant...