4-Bromo-N,N-dimethylaniline

Names

[ CAS No. ]:
586-77-6

[ Name ]:
4-Bromo-N,N-dimethylaniline

[Synonym ]:
N-(4-bromophenyl)-N,N-dimethylamine
p-(Dimethylamino)phenyl bromide
N,N-Dimethyl-p-bromoaniline
Benzenamine, 4-bromo-N,N-dimethyl-
Benzenamine,4-bromo-N,N-dimethyl
EINECS 209-582-2
4-Bromo-N,N-dimethylbenzenamine
4-N,N-dimethylaminobromobenzene
MFCD00000093
(4-bromophenyl)dimethylamine
N,N-Dimethyl-4-bromoaniline
1-bromo-4-dimethylaminobenzene
p-Bromo-N,N-dimethylaniline
N,N-(dimethylamino)-4-bromobenzene
p-Dimethylaminobromobenzene
4-Bromo-N,N-dimethylaniline
4-bromo-N,N-dimethyl-aniline
(4-bromo-phenyl)-dimethylamine
4-dimethylamino-1-bromobenzene
4-Dimethylaminobromobenzene

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
264.0±0.0 °C at 760 mmHg

[ Melting Point ]:
52-54 °C(lit.)

[ Molecular Formula ]:
C₈H₁₀BrN

[ Molecular Weight ]:
200.076

[ Flash Point ]:
104.7±19.8 °C

[ Exact Mass ]:
198.999649

[ PSA ]:
3.24000

[ LogP ]:
3.34

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.587

[ Stability ]:
Stable. Incompatible with oxidizing agents, acids, metals.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BW9300000

CHEMICAL NAME :: Aniline, 4-bromo-N,N-dimethyl-

CAS REGISTRY NUMBER :: 586-77-6

LAST UPDATED :: 199709

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C8-H10-Br-N

MOLECULAR WEIGHT :: 200.10

WISWESSER LINE NOTATION :: ER DN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 90,260,1947

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H312 + H332-H315-H319

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R33

[ Safety Phrases ]:
S26-S36-S45-S37-S28A

[ RIDADR ]:
2811

[ WGK Germany ]:
3

[ RTECS ]:
BW9300000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2921499090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2921420090

[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Redox inactive metal ion triggered N-dealkylation by an iron catalyst with dioxygen activation: a lesson from lipoxygenases.

Dalton Trans. 44 , 9847-59, (2015)

Utilization of dioxygen as the terminal oxidant at ambient temperature is always a challenge in redox chemistry, because it is hard to oxidize a stable redox metal ion like iron(III) to its high oxida...

Single drop microextraction or solid phase microextraction-gas chromatography-mass spectrometry for the determination of iodine in pharmaceuticals, iodized salt, milk powder and vegetables involving conversion into 4-iodo-N,N-dimethylaniline.

J. Chromatogr. A. 1023(1) , 33-9, (2004)

A rapid sequence of oxidation and iodination using 2-iodosobenzoate as an oxidizing agent and N,N-dimethylaniline as an iodine scavenger at pH 6.4, when 4-iodo-N,N-dimethylaniline is formed, has been ...