3-Hydroxycinnamic acid

Names

[ CAS No. ]:
588-30-7

[ Name ]:
3-Hydroxycinnamic acid

[Synonym ]:
M-COUMARIC ACID
2-Propenoic acid, 3-(3-hydroxyphenyl)-
RARECHEM BK HC T323
MFCD00004390
3-(3-Hydroxyphenyl)acrylic acid
COUMARIC ACID,3
TRANS-M-COUMARIC ACID
TRANS-M-CUMARIC ACID
EINECS 209-615-0
COUMARIC ACID,3-(RG)
Cinnamic acid, m-hydroxy-
3-Hydroxycinnamic acid

Biological Activity

[Description]:

m-Coumaric acid is a polyphenol metabolite from caffeic acid, formed by the gut microflora and the amount in human biofluids is diet-dependant.

[Related Catalog]:

Natural Products >> Acids and Aldehydes

Research Areas >> Others

[Target]

Human Endogenous Metabolite

[References]

[1]. Ito H, et al. Chlorogenic acid and its metabolite m-coumaric acid evoke neurite outgrowth in hippocampal neuronal cells. Biosci Biotechnol Biochem. 2008 Mar;72(3):885-8.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
373.2±25.0 °C at 760 mmHg

[ Melting Point ]:
193-195ºC(lit.)

[ Molecular Formula ]:
C₉H₈O₃

[ Molecular Weight ]:
164.158

[ Flash Point ]:
193.7±19.7 °C

[ Exact Mass ]:
164.047348

[ PSA ]:
57.53000

[ LogP ]:
1.83

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.660

[ Storage condition ]:
-20℃

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22-S24/25-S36-S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Antimicrobial activity of natural products from the flora of Northern Ontario, Canada.

Pharm. Biol. 53(6) , 800-6, (2015)

The number of multidrug resistant (MDR) microorganisms is increasing and the antimicrobial resistance expressed by these pathogens is generating a rising global health crisis. In fact, there are only ...

The tomato sauce making process affects the bioaccessibility and bioavailability of tomato phenolics: a pharmacokinetic study.

Food Chem. 173 , 864-72, (2014)

Tomato sauce is the most commonly consumed processed tomato product worldwide, but very little is known about how the manufacturing process may affect the phenolic composition and bioavailability afte...

Development of a targeted method for twenty-three metabolites related to polyphenol gut microbial metabolism in biological samples, using SPE and UHPLC-ESI-MS/MS.

Talanta 128 , 221-30, (2014)

An increasing number of studies have concerned the profiling of polyphenol microbial metabolites, especially in urine or plasma, but only a few have regarded their accurate quantification. This study ...