3-Bromopropanoic acid
Names
[ CAS No. ]:
590-92-1
[ Name ]:
3-Bromopropanoic acid
[Synonym ]:
β-Bromopropanoic acid
EINECS 209-694-1
3-Bromopropionic acid
MFCD00002763
Propanoic acid, 3-bromo-
3-Bromopropanoic acid
PROPIONIC ACID, 3-BROMO-
β-Bromopropionic acid
3-Bromopropionic
Chemical & Physical Properties
[ Density]:
1.8±0.1 g/cm3
[ Boiling Point ]:
239.5±23.0 °C at 760 mmHg
[ Melting Point ]:
58-62 °C(lit.)
[ Molecular Formula ]:
C3H5BrO2
[ Molecular Weight ]:
152.975
[ Flash Point ]:
65.6±0.0 °C
[ Exact Mass ]:
151.947281
[ PSA ]:
37.30000
[ LogP ]:
0.69
[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C
[ Index of Refraction ]:
1.500
[ Water Solubility ]:
0.1 g/mL
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UE7875000
- CHEMICAL NAME :
- Propionic acid, 3-bromo-
- CAS REGISTRY NUMBER :
- 590-92-1
- BEILSTEIN REFERENCE NO. :
- 1071333
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C3-H5-Br-O2
- MOLECULAR WEIGHT :
- 152.99
- WISWESSER LINE NOTATION :
- QV2E
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 580 mg/kg/8W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 25 ug/plate
- REFERENCE :
- DHEFDK HEW Publication (FDA. United States). (Washington, DC) ?-1979(?). For publisher information, see HPFSDS. Volume(issue)/page/year: FDA-78-1046,1978
Safety Information
[ Symbol ]:
GHS05
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H314
[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
F:Flammable;C:Corrosive;
[ Risk Phrases ]:
R11;R34
[ Safety Phrases ]:
S26-S36/37/39-S45
[ RIDADR ]:
UN 3261 8/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
UE7875000
[ Packaging Group ]:
III
[ Hazard Class ]:
4.1
[ HS Code ]:
2915501000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2915900090
[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%
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An accurate and precise method was developed for the detection and quantification of 3-bromopropionic acid (3-BPA), a metabolite and biomarker for exposure to 1-bromopropane (1-BP). 1-BP is used as an...