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α-Endorphin

Names

[ CAS No. ]:
59004-96-5

[ Name ]:
α-Endorphin

[Synonym ]:
YGGFMTSEKSQTPLVT
alpha-Endorphin
LPH(61-76)
a-Endorphin
A-ENDORPHIN HUMAN
EINECS 262-330-3
MFCD00076381
Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr
YGGFMTSEKSQTPLVTLFKNAIIKNAYKKGE

Chemical & Physical Properties

[ Molecular Formula ]:
C77H120N18O26S

[ Molecular Weight ]:
1745.95000

[ Exact Mass ]:
1744.83000

[ PSA ]:
744.12000

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Live cell monitoring of mu-opioid receptor-mediated G-protein activation reveals strong biological activity of close morphine biosynthetic precursors.

J. Biol. Chem. 282 , 27126-32, (2007)

G-protein activation by receptors is generally measured using (35)S-GTPgammaS binding assays in cell membranes and cannot be well assessed in intact cells. We have recently developed a fluorescence re...

gamma endorphin, alpha endorphin and Met-enkephalin are formed extracellularly from lipotropin C fragment.

Nature 269(5629) , 619-21, (1977)

Selective conversion of beta-endorphin into peptides related to gamma- and alpha-endorphin.

Nature 283(5742) , 96-7, (1980)

beta-Endorphin (beta-LPH61-91) is a well known endogenous opioid ligand. It and related peptides have recently been implicated in the control of adaptive behaviour. Smaller beta-endorphin fragments ap...


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Related Compounds