Ethyl 4-chloro-2-Methylthio-5-pyriMidinecarboxylate

Names

[ Name ]:
Ethyl 4-chloro-2-Methylthio-5-pyriMidinecarboxylate

[Synonym ]:
Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate
EINECS 227-619-0
Ethyl 4-chloro-2-(methylsulfanyl)-5-pyrimidinecarboxylate
ethyl 4-chloro-2-(methylsulfanyl)pyrimidine-5-carboxylate
Ethyl 4-chloro-2-(methylthio)-5-pyrimidinecarboxylate
MFCD00006085
4-chloro-2-(methylthio)pyrimidine-5-carboxylic acid ethyl ester
4-chloro-5-carbethoxy-2-methylthiopyrimidine
5-Pyrimidinecarboxylic acid, 4-chloro-2-(methylthio)-, ethyl ester
Ethyl-4-chlor-2-(methylsulfanyl)pyrimidin-5-carboxylat
5-Pyrimidinecarboxylic acid, 4-chloro-2- (methylthio)-, ethyl ester
ethyl 4-chloro-2-methylsulfanylpyrimidine-5-carboxylate
ethyl4-chloro-2-(methylthio)pyrimidine-5-carboxylate

Biological Activity

[Description]:

Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
335.7±22.0 °C at 760 mmHg

[ Melting Point ]:
60-63 °C(lit.)

[ Molecular Formula ]:
C₈H₉ClN₂O₂S

[ Molecular Weight ]:
232.687

[ Flash Point ]:
156.8±22.3 °C

[ Exact Mass ]:
232.007324

[ PSA ]:
77.38000

[ LogP ]:
2.55

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.568

[ Storage condition ]:
Keep Cold

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Design and synthesis of a pyrido[2,3-d]pyrimidin-5-one class of anti-inflammatory FMS inhibitors.

Bioorg. Med. Chem. Lett. 18(7) , 2355-61, (2008)

A series of pyrimidinopyridones has been designed, synthesized and shown to be potent and selective inhibitors of the FMS tyrosine kinase. Introduction of an amide substituent at the 6-position of the...