(9S)-Cinchonan-9-ol sulfate (2:1)

Names

[ Name ]:
(9S)-Cinchonan-9-ol sulfate (2:1)

[Synonym ]:
Cinchonan-9-ol, (9S)-, sulfate (2:1) (salt)
(9S)-Cinchonan-9-ol sulfate (2:1)
EINECS 227-708-4
MFCD00035639
cinchonine sulfate

Chemical & Physical Properties

[ Density]:
1.61g/cm3

[ Boiling Point ]:
169 °C(lit.)

[ Melting Point ]:
38-40 °C(lit.)

[ Molecular Formula ]:
C₃₈H₄₆N₄O₆S

[ Molecular Weight ]:
686.860

[ Flash Point ]:
148 °F

[ Exact Mass ]:
686.313782

[ PSA ]:
155.70000

[ LogP ]:
6.63300

[ Index of Refraction ]:
1.717

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GD3800000

CAS REGISTRY NUMBER :: 5949-16-6

LAST UPDATED :: 198708

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C19-H22-N2-O.1/2H2-O4-S

MOLECULAR WEIGHT :: 343.43

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 78,159,1943

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
1544

[ WGK Germany ]:
3

[ RTECS ]:
GD3800000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

Articles

Mutation in the Plasmodium falciparum CRT protein determines the stereospecific activity of antimalarial cinchona alkaloids.

Antimicrob. Agents Chemother. 56(10) , 5356-64, (2012)

The Cinchona alkaloids are quinoline aminoalcohols that occur as diastereomer pairs, typified by (-)-quinine and (+)-quinidine. The potency of (+)-isomers is greater than the (-)-isomers in vitro and ...

A theoretical investigation on the Strecker reaction catalyzed by a Ti(IV)-complex catalyst generated from a cinchona alkaloid, achiral substituted 2,2'-biphenol, and tetraisopropyl titanate.

Chemistry 19(5) , 1637-46, (2013)

The mechanism and the origin of selectivity of the asymmetric Strecker reaction catalyzed by a Ti(IV)-complex catalyst generated from a cinchona alkaloid, achiral substituted 2,2'-biphenol, and tetrai...

Organocatalytic asymmetric conjugate addition of 3-monosubstituted oxindoles to (E)-1,4-diaryl-2-buten-1,4-diones: a strategy for the indirect enantioselective furanylation and pyrrolylation of 3-alkyloxindoles.

Chemistry 18(21) , 6679-87, (2012)

An asymmetric conjugate addition of 3-monosubstituted oxindoles to a range of (E)-1,4-diaryl-2-buten-1,4-diones, catalyzed by commercially available cinchonine, is described. This organocatalytic asym...